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IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2

The prognosis of glioblastoma (GBM) patients is poor, and temozolomide (TMZ) resistance has become an important obstacle to its treatment effect. A growing number of researches have revealed the special characteristics of iron metabolism in GBM chemosensitivity. Iron regulatory protein 1 (IRP1) is a...

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Detalles Bibliográficos
Autores principales:	Lan, Yufei, Yang, Tao, Yue, Qu, Wang, Zhao, Zhong, Xiangyang, Luo, Xin, Zuo, Boming, Zhang, Manqing, Zeng, Tianci, Liu, Boyang, Guo, Hongbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374607/ https://www.ncbi.nlm.nih.gov/pubmed/37520713 http://dx.doi.org/10.1016/j.isci.2023.107377

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