Metabolic reprogramming of proinflammatory macrophages by target delivered roburic acid effectively ameliorates rheumatoid arthritis symptoms

Rheumatoid arthritis (RA) is a common chronic inflammatory disorder that usually affects joints. It was found that roburic acid (RBA), an ingredient from anti-RA herb Gentiana macrophylla Pall., displayed strong anti-inflammatory activity. However, its medical application is limited by its hydrophob...

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Detalles Bibliográficos
Autores principales: Jia, Na, Gao, Yunzhen, Li, Min, Liang, Yi, Li, Yuwen, Lin, Yunzhu, Huang, Shiqi, Lin, Qing, Sun, Xun, He, Qin, Yao, Yuqin, Zhang, Ben, Zhang, Zhirong, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374631/
https://www.ncbi.nlm.nih.gov/pubmed/37500654
http://dx.doi.org/10.1038/s41392-023-01499-0

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