Loss of N-terminal acetyltransferase A activity induces thermally unstable ribosomal proteins and increases their turnover in Saccharomyces cerevisiae

Protein N-terminal (Nt) acetylation is one of the most abundant modifications in eukaryotes, covering ~50-80 % of the proteome, depending on species. Cells with defective Nt-acetylation display a wide array of phenotypes such as impaired growth, mating defects and increased stress sensitivity. Howev...

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Detalles Bibliográficos
Autores principales: Guzman, Ulises H., Aksnes, Henriette, Ree, Rasmus, Krogh, Nicolai, Jakobsson, Magnus E., Jensen, Lars J., Arnesen, Thomas, Olsen, Jesper V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374663/
https://www.ncbi.nlm.nih.gov/pubmed/37500638
http://dx.doi.org/10.1038/s41467-023-40224-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374663/
https://www.ncbi.nlm.nih.gov/pubmed/37500638
http://dx.doi.org/10.1038/s41467-023-40224-x

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