Inhibitory effects of NSAID-conjugated SN-38 on the viability of A549 Non-small cell lung cancer cells

The goal of this paper was to look into the anti-tumor mechanism of Non-Steroidal Anti-Inflammatory Drug (NSAID)-conjugated SN-38 Prodrug in A549 lung cancer cells. We found that Indomethacine–SN–38 (IndoSN-38) and Naproxen–SN–38(NaproSN-38) as a theranostic prodrug targeting cyclooxygenase-2(COX-2)...

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Detalles Bibliográficos
Autores principales: Kwon, Hae–Won, An, Jusung, Kim, Jong Seung, Kang, In-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374863/
https://www.ncbi.nlm.nih.gov/pubmed/37521373
http://dx.doi.org/10.1016/j.bbrep.2023.101517

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