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A case report of liver abscesses caused by Fusobacterium necrophorum in immunocompetent patient and review of the literature

BACKGROUND: Fusobacterium necrophorum is an anaerobic Gram-negative bacterium that can lead to opportunistic infections, including Lemierre's syndrome and less common presentations of metastatic diseases. However, liver abscesses infected by Fusobacterium necrophorum in clinical settings are ra...

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Autores principales: Zhang, Xiaoqiang, Jiyun Zhou, Yinhong Zhu, Ye, Xufang, Bo, Dehua, Tianjiao Tang, Huang, Xiaojing, Qu, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374925/
https://www.ncbi.nlm.nih.gov/pubmed/37520974
http://dx.doi.org/10.1016/j.heliyon.2023.e18535
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author Zhang, Xiaoqiang
Jiyun Zhou
Yinhong Zhu
Ye, Xufang
Bo, Dehua
Tianjiao Tang
Huang, Xiaojing
Qu, Tingting
author_facet Zhang, Xiaoqiang
Jiyun Zhou
Yinhong Zhu
Ye, Xufang
Bo, Dehua
Tianjiao Tang
Huang, Xiaojing
Qu, Tingting
author_sort Zhang, Xiaoqiang
collection PubMed
description BACKGROUND: Fusobacterium necrophorum is an anaerobic Gram-negative bacterium that can lead to opportunistic infections, including Lemierre's syndrome and less common presentations of metastatic diseases. However, liver abscesses infected by Fusobacterium necrophorum in clinical settings are rarely reported, particularly in people with normal immune function. CASE PRESENTATION: A 35-year-old Chinese man was admitted with hyperthermia and abdominal pain that had persisted for three days. The patient continued to have a fever with a maximum temperature of 39.8 °C during hospitalization. Computed Tomography revealed multiple low-density lesions in the liver, which were diagnosed as liver abscesses caused by Fusobacterium necrophorum infection through blood culture and anaerobic liver abscess fluid culture. After simple local percutaneous abscess drainage and effective anti-infective therapy, the patient achieved complete remission. CONCLUSIONS: Results of our literature search query revealed rare reports of liver abscesses infected by Fusobacterium necrophorum. We recommend that Fusobacterium necrophorum infection be considered in diagnosis special situations of liver abscess.
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spelling pubmed-103749252023-07-29 A case report of liver abscesses caused by Fusobacterium necrophorum in immunocompetent patient and review of the literature Zhang, Xiaoqiang Jiyun Zhou Yinhong Zhu Ye, Xufang Bo, Dehua Tianjiao Tang Huang, Xiaojing Qu, Tingting Heliyon Case Report BACKGROUND: Fusobacterium necrophorum is an anaerobic Gram-negative bacterium that can lead to opportunistic infections, including Lemierre's syndrome and less common presentations of metastatic diseases. However, liver abscesses infected by Fusobacterium necrophorum in clinical settings are rarely reported, particularly in people with normal immune function. CASE PRESENTATION: A 35-year-old Chinese man was admitted with hyperthermia and abdominal pain that had persisted for three days. The patient continued to have a fever with a maximum temperature of 39.8 °C during hospitalization. Computed Tomography revealed multiple low-density lesions in the liver, which were diagnosed as liver abscesses caused by Fusobacterium necrophorum infection through blood culture and anaerobic liver abscess fluid culture. After simple local percutaneous abscess drainage and effective anti-infective therapy, the patient achieved complete remission. CONCLUSIONS: Results of our literature search query revealed rare reports of liver abscesses infected by Fusobacterium necrophorum. We recommend that Fusobacterium necrophorum infection be considered in diagnosis special situations of liver abscess. Elsevier 2023-07-21 /pmc/articles/PMC10374925/ /pubmed/37520974 http://dx.doi.org/10.1016/j.heliyon.2023.e18535 Text en © 2023 The Authors. Published by Elsevier Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Zhang, Xiaoqiang
Jiyun Zhou
Yinhong Zhu
Ye, Xufang
Bo, Dehua
Tianjiao Tang
Huang, Xiaojing
Qu, Tingting
A case report of liver abscesses caused by Fusobacterium necrophorum in immunocompetent patient and review of the literature
title A case report of liver abscesses caused by Fusobacterium necrophorum in immunocompetent patient and review of the literature
title_full A case report of liver abscesses caused by Fusobacterium necrophorum in immunocompetent patient and review of the literature
title_fullStr A case report of liver abscesses caused by Fusobacterium necrophorum in immunocompetent patient and review of the literature
title_full_unstemmed A case report of liver abscesses caused by Fusobacterium necrophorum in immunocompetent patient and review of the literature
title_short A case report of liver abscesses caused by Fusobacterium necrophorum in immunocompetent patient and review of the literature
title_sort case report of liver abscesses caused by fusobacterium necrophorum in immunocompetent patient and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374925/
https://www.ncbi.nlm.nih.gov/pubmed/37520974
http://dx.doi.org/10.1016/j.heliyon.2023.e18535
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