Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis

The functional association between stimulation of G-protein–coupled receptors (GPCRs) by eicosanoids and actin cytoskeleton reorganization remains largely unexplored. Using a model of human adrenocortical cancer cells, here we established that activation of the GPCR OXER1 by its natural agonist, the...

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Detalles Bibliográficos
Autores principales: Cooke, Mariana, Zhang, Suli, Cornejo Maciel, Fabiana, Kazanietz, Marcelo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
JBC Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374973/
https://www.ncbi.nlm.nih.gov/pubmed/37390986
http://dx.doi.org/10.1016/j.jbc.2023.104983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374973/
https://www.ncbi.nlm.nih.gov/pubmed/37390986
http://dx.doi.org/10.1016/j.jbc.2023.104983

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