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Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
The functional association between stimulation of G-protein–coupled receptors (GPCRs) by eicosanoids and actin cytoskeleton reorganization remains largely unexplored. Using a model of human adrenocortical cancer cells, here we established that activation of the GPCR OXER1 by its natural agonist, the...
Autores principales: | Cooke, Mariana, Zhang, Suli, Cornejo Maciel, Fabiana, Kazanietz, Marcelo G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374973/ https://www.ncbi.nlm.nih.gov/pubmed/37390986 http://dx.doi.org/10.1016/j.jbc.2023.104983 |
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