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From barriers to novel strategies: smarter CAR T therapy hits hard to tumors

Chimeric antigen receptor (CAR) T cell therapy for solid tumors shows promise, but several hurdles remain. Strategies to overcome barriers such as CAR T therapy-related toxicities (CTT), immunosuppression, and immune checkpoints through research and technology are needed to put the last nail to the...

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Detalles Bibliográficos
Autores principales: Khawar, Muhammad Babar, Ge, Fei, Afzal, Ali, Sun, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375020/
https://www.ncbi.nlm.nih.gov/pubmed/37520522
http://dx.doi.org/10.3389/fimmu.2023.1203230