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Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal

Background : Seasonal malaria chemoprevention (SMC) has been adopted and implemented in the southern regions of Senegal in children aged between three and 120 months since 2013. Scaling up this strategy requires its evaluation to assess the impact. This study was carried out to determine the dynamic...

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Autores principales: Manga, Isaac Akhenaton, BA, Mamadou Sarifou, Tairou, Fassiatou, Seck, Amadou, Kouevidjin, Ekoue, Sow, Doudou, Sylla, Khadime, Ndiaye, Magatte, Ba Fall, Fatou, Gueye, Alioune Babara, Diallo, Ibrahima, Ndiop, Médoune, Ba, Mady, Tine, Roger Clément, Gaye, Omar, Faye, Babacar, Ndiaye, Jean Louis Abdourahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375055/
https://www.ncbi.nlm.nih.gov/pubmed/37521536
http://dx.doi.org/10.12688/wellcomeopenres.17888.2
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author Manga, Isaac Akhenaton
BA, Mamadou Sarifou
Tairou, Fassiatou
Seck, Amadou
Kouevidjin, Ekoue
Sow, Doudou
Sylla, Khadime
Ndiaye, Magatte
Ba Fall, Fatou
Gueye, Alioune Babara
Diallo, Ibrahima
Ndiop, Médoune
Ba, Mady
Tine, Roger Clément
Gaye, Omar
Faye, Babacar
Ndiaye, Jean Louis Abdourahim
author_facet Manga, Isaac Akhenaton
BA, Mamadou Sarifou
Tairou, Fassiatou
Seck, Amadou
Kouevidjin, Ekoue
Sow, Doudou
Sylla, Khadime
Ndiaye, Magatte
Ba Fall, Fatou
Gueye, Alioune Babara
Diallo, Ibrahima
Ndiop, Médoune
Ba, Mady
Tine, Roger Clément
Gaye, Omar
Faye, Babacar
Ndiaye, Jean Louis Abdourahim
author_sort Manga, Isaac Akhenaton
collection PubMed
description Background : Seasonal malaria chemoprevention (SMC) has been adopted and implemented in the southern regions of Senegal in children aged between three and 120 months since 2013. Scaling up this strategy requires its evaluation to assess the impact. This study was carried out to determine the dynamics of Plasmodium falciparum carriage before and after two years of SMC implementation. Methods : Four household surveys were conducted in villages in the health district of Saraya, which is a SMC implementation area in Senegal. These villages were selected using probability proportional to size sampling. Each selected village was divided into segments containing at least 50 children. In each segment, a household questionnaire was administered to the parents or legal representatives of children aged three to 120 months. Blood smears were collected to determine P. falciparum prevalence by microscopy one month before the first round of SMC, one month after the last round of the first SMC campaign and two years after the start of the implementation. Results : A total of 2008 children were included with a mean average age of 4.81 (+/-2.73) years. Of the study population, 50.33% were more than five years old and 50.3% were male. In 2013, mosquito net ownership was 99.4 % before the SMC campaign and 97.4% after. In 2015, it was 36.6% before and 45.8% after the campaign. In 2013, the prevalence of plasmodium carriage was 11.8% before and 6.1% after the SMC campaign. In 2015, the prevalence was 4.9% before the administration of SMC and this increased up to 15.3% after. Malaria prevalence was high among children over five years old and in boys. Conclusions : The decrease in Plasmodium falciparum parasite prevalence, which subsequently increased after two years of SMC implementation in this study, suggests adding an extra cycle of the SMC or adjusting the administration period.
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spelling pubmed-103750552023-07-29 Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal Manga, Isaac Akhenaton BA, Mamadou Sarifou Tairou, Fassiatou Seck, Amadou Kouevidjin, Ekoue Sow, Doudou Sylla, Khadime Ndiaye, Magatte Ba Fall, Fatou Gueye, Alioune Babara Diallo, Ibrahima Ndiop, Médoune Ba, Mady Tine, Roger Clément Gaye, Omar Faye, Babacar Ndiaye, Jean Louis Abdourahim Wellcome Open Res Research Article Background : Seasonal malaria chemoprevention (SMC) has been adopted and implemented in the southern regions of Senegal in children aged between three and 120 months since 2013. Scaling up this strategy requires its evaluation to assess the impact. This study was carried out to determine the dynamics of Plasmodium falciparum carriage before and after two years of SMC implementation. Methods : Four household surveys were conducted in villages in the health district of Saraya, which is a SMC implementation area in Senegal. These villages were selected using probability proportional to size sampling. Each selected village was divided into segments containing at least 50 children. In each segment, a household questionnaire was administered to the parents or legal representatives of children aged three to 120 months. Blood smears were collected to determine P. falciparum prevalence by microscopy one month before the first round of SMC, one month after the last round of the first SMC campaign and two years after the start of the implementation. Results : A total of 2008 children were included with a mean average age of 4.81 (+/-2.73) years. Of the study population, 50.33% were more than five years old and 50.3% were male. In 2013, mosquito net ownership was 99.4 % before the SMC campaign and 97.4% after. In 2015, it was 36.6% before and 45.8% after the campaign. In 2013, the prevalence of plasmodium carriage was 11.8% before and 6.1% after the SMC campaign. In 2015, the prevalence was 4.9% before the administration of SMC and this increased up to 15.3% after. Malaria prevalence was high among children over five years old and in boys. Conclusions : The decrease in Plasmodium falciparum parasite prevalence, which subsequently increased after two years of SMC implementation in this study, suggests adding an extra cycle of the SMC or adjusting the administration period. F1000 Research Limited 2022-10-11 /pmc/articles/PMC10375055/ /pubmed/37521536 http://dx.doi.org/10.12688/wellcomeopenres.17888.2 Text en Copyright: © 2022 Manga IA et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Manga, Isaac Akhenaton
BA, Mamadou Sarifou
Tairou, Fassiatou
Seck, Amadou
Kouevidjin, Ekoue
Sow, Doudou
Sylla, Khadime
Ndiaye, Magatte
Ba Fall, Fatou
Gueye, Alioune Babara
Diallo, Ibrahima
Ndiop, Médoune
Ba, Mady
Tine, Roger Clément
Gaye, Omar
Faye, Babacar
Ndiaye, Jean Louis Abdourahim
Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal
title Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal
title_full Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal
title_fullStr Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal
title_full_unstemmed Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal
title_short Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal
title_sort malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the saraya health district, southern senegal
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375055/
https://www.ncbi.nlm.nih.gov/pubmed/37521536
http://dx.doi.org/10.12688/wellcomeopenres.17888.2
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