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Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte (Adv. Sci. 21/2023)
Beige Adipocyte Beige fat is gaining increasing therapeutic interest due to its potential in combating obesity and other non‐communicable diseases. By single clone analysis, Tao Nie, Donghai Wu, Hannah Xiaoyan Hui, and co‐workers discover that androgen receptor (AR) turns out to be a highly potent t...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375141/ http://dx.doi.org/10.1002/advs.202370137 |
| _version_ | 1785078970305216512 |
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| author | Zhao, Shiting Nie, Tao Li, Lei Long, Qiaoyun Gu, Ping Zhang, Yuwei Sun, Wei Lin, Zexin Liu, Qing Qi, Yue Wang, Wei Xie, Mengyuan Loomes, Kerry Cai, Chenleng Wu, Donghai Hui, Hannah Xiaoyan |
| author_facet | Zhao, Shiting Nie, Tao Li, Lei Long, Qiaoyun Gu, Ping Zhang, Yuwei Sun, Wei Lin, Zexin Liu, Qing Qi, Yue Wang, Wei Xie, Mengyuan Loomes, Kerry Cai, Chenleng Wu, Donghai Hui, Hannah Xiaoyan |
| author_sort | Zhao, Shiting |
| collection | PubMed |
| description | Beige Adipocyte Beige fat is gaining increasing therapeutic interest due to its potential in combating obesity and other non‐communicable diseases. By single clone analysis, Tao Nie, Donghai Wu, Hannah Xiaoyan Hui, and co‐workers discover that androgen receptor (AR) turns out to be a highly potent transcription factor in suppression of PRDM16, the key molecular switch of beige fat. The article number 2300070 provides new insight in explaining the sex difference in beige fat activity in human and may shed light on sex hormone‐related therapies. [Image: see text] |
| format | Online Article Text |
| id | pubmed-10375141 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-103751412023-07-29 Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte (Adv. Sci. 21/2023) Zhao, Shiting Nie, Tao Li, Lei Long, Qiaoyun Gu, Ping Zhang, Yuwei Sun, Wei Lin, Zexin Liu, Qing Qi, Yue Wang, Wei Xie, Mengyuan Loomes, Kerry Cai, Chenleng Wu, Donghai Hui, Hannah Xiaoyan Adv Sci (Weinh) Frontispiece Beige Adipocyte Beige fat is gaining increasing therapeutic interest due to its potential in combating obesity and other non‐communicable diseases. By single clone analysis, Tao Nie, Donghai Wu, Hannah Xiaoyan Hui, and co‐workers discover that androgen receptor (AR) turns out to be a highly potent transcription factor in suppression of PRDM16, the key molecular switch of beige fat. The article number 2300070 provides new insight in explaining the sex difference in beige fat activity in human and may shed light on sex hormone‐related therapies. [Image: see text] John Wiley and Sons Inc. 2023-07-27 /pmc/articles/PMC10375141/ http://dx.doi.org/10.1002/advs.202370137 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
| spellingShingle | Frontispiece Zhao, Shiting Nie, Tao Li, Lei Long, Qiaoyun Gu, Ping Zhang, Yuwei Sun, Wei Lin, Zexin Liu, Qing Qi, Yue Wang, Wei Xie, Mengyuan Loomes, Kerry Cai, Chenleng Wu, Donghai Hui, Hannah Xiaoyan Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte (Adv. Sci. 21/2023) |
| title | Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte (Adv. Sci. 21/2023) |
| title_full | Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte (Adv. Sci. 21/2023) |
| title_fullStr | Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte (Adv. Sci. 21/2023) |
| title_full_unstemmed | Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte (Adv. Sci. 21/2023) |
| title_short | Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte (Adv. Sci. 21/2023) |
| title_sort | androgen receptor is a negative regulator of prdm16 in beige adipocyte (adv. sci. 21/2023) |
| topic | Frontispiece |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375141/ http://dx.doi.org/10.1002/advs.202370137 |
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