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Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles (Adv. Sci. 21/2023)
Targeted LNPs Delivery to the Bone Marrow In article number 2301377, Dana Tarab‐Ravski, Dan Peer, and co‐workers develop targeted lipid nanoparticles to efficiently deliver therapeutic RNA to multiple myeloma cells in the bone marrow. In a novel xenograft multiple myeloma (MM) mouse model, this deli...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375169/ http://dx.doi.org/10.1002/advs.202370141 |
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author | Tarab‐Ravski, Dana Hazan‐Halevy, Inbal Goldsmith, Meir Stotsky‐Oterin, Lior Breier, Dor Naidu, Gonna Somu Aitha, Anjaiah Diesendruck, Yael Ng, Brandon D. Barsheshet, Hagit Berger, Tamar Vaxman, Iuliana Raanani, Pia Peer, Dan |
author_facet | Tarab‐Ravski, Dana Hazan‐Halevy, Inbal Goldsmith, Meir Stotsky‐Oterin, Lior Breier, Dor Naidu, Gonna Somu Aitha, Anjaiah Diesendruck, Yael Ng, Brandon D. Barsheshet, Hagit Berger, Tamar Vaxman, Iuliana Raanani, Pia Peer, Dan |
author_sort | Tarab‐Ravski, Dana |
collection | PubMed |
description | Targeted LNPs Delivery to the Bone Marrow In article number 2301377, Dana Tarab‐Ravski, Dan Peer, and co‐workers develop targeted lipid nanoparticles to efficiently deliver therapeutic RNA to multiple myeloma cells in the bone marrow. In a novel xenograft multiple myeloma (MM) mouse model, this delivery system demonstrates its ability to specifically target MM cells and produce a positive clinical outcome in mice engrafted with MM. [Image: see text] |
format | Online Article Text |
id | pubmed-10375169 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103751692023-07-29 Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles (Adv. Sci. 21/2023) Tarab‐Ravski, Dana Hazan‐Halevy, Inbal Goldsmith, Meir Stotsky‐Oterin, Lior Breier, Dor Naidu, Gonna Somu Aitha, Anjaiah Diesendruck, Yael Ng, Brandon D. Barsheshet, Hagit Berger, Tamar Vaxman, Iuliana Raanani, Pia Peer, Dan Adv Sci (Weinh) Inside Back Cover Targeted LNPs Delivery to the Bone Marrow In article number 2301377, Dana Tarab‐Ravski, Dan Peer, and co‐workers develop targeted lipid nanoparticles to efficiently deliver therapeutic RNA to multiple myeloma cells in the bone marrow. In a novel xenograft multiple myeloma (MM) mouse model, this delivery system demonstrates its ability to specifically target MM cells and produce a positive clinical outcome in mice engrafted with MM. [Image: see text] John Wiley and Sons Inc. 2023-07-27 /pmc/articles/PMC10375169/ http://dx.doi.org/10.1002/advs.202370141 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Inside Back Cover Tarab‐Ravski, Dana Hazan‐Halevy, Inbal Goldsmith, Meir Stotsky‐Oterin, Lior Breier, Dor Naidu, Gonna Somu Aitha, Anjaiah Diesendruck, Yael Ng, Brandon D. Barsheshet, Hagit Berger, Tamar Vaxman, Iuliana Raanani, Pia Peer, Dan Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles (Adv. Sci. 21/2023) |
title | Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles (Adv. Sci. 21/2023) |
title_full | Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles (Adv. Sci. 21/2023) |
title_fullStr | Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles (Adv. Sci. 21/2023) |
title_full_unstemmed | Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles (Adv. Sci. 21/2023) |
title_short | Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles (Adv. Sci. 21/2023) |
title_sort | delivery of therapeutic rna to the bone marrow in multiple myeloma using cd38‐targeted lipid nanoparticles (adv. sci. 21/2023) |
topic | Inside Back Cover |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375169/ http://dx.doi.org/10.1002/advs.202370141 |
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