Cargando…

Preference of Bacterial Rhamnosyltransferases for 6-Deoxysugars Reveals a Strategy To Deplete O-Antigens

[Image: see text] Bacteria synthesize hundreds of bacteria-specific or “rare” sugars that are absent in mammalian cells and enriched in 6-deoxy monosaccharides such as l-rhamnose (l-Rha). Across bacteria, l-Rha is incorporated into glycans by rhamnosyltransferases (RTs) that couple nucleotide sugar...

Descripción completa

Detalles Bibliográficos
Autores principales: Harnagel, Alexa P., Sheshova, Mia, Zheng, Meng, Zheng, Maggie, Skorupinska-Tudek, Karolina, Swiezewska, Ewa, Lupoli, Tania J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375533/
https://www.ncbi.nlm.nih.gov/pubmed/37437030
http://dx.doi.org/10.1021/jacs.3c03005

Ejemplares similares