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Preference of Bacterial Rhamnosyltransferases for 6-Deoxysugars Reveals a Strategy To Deplete O-Antigens
[Image: see text] Bacteria synthesize hundreds of bacteria-specific or “rare” sugars that are absent in mammalian cells and enriched in 6-deoxy monosaccharides such as l-rhamnose (l-Rha). Across bacteria, l-Rha is incorporated into glycans by rhamnosyltransferases (RTs) that couple nucleotide sugar...
Autores principales: | Harnagel, Alexa P., Sheshova, Mia, Zheng, Meng, Zheng, Maggie, Skorupinska-Tudek, Karolina, Swiezewska, Ewa, Lupoli, Tania J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375533/ https://www.ncbi.nlm.nih.gov/pubmed/37437030 http://dx.doi.org/10.1021/jacs.3c03005 |
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