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Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam-matched linacs: a three-institutional study

BACKGROUND: Beam matching is a concept in radiotherapy applied to clinics where more than one linac is employed to harmonise beam characteristics across linacs for allowing patients interchange without replanning. In view of this, the current study analyzes and compares dosimetric characteristics of...

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Autores principales: Ghemiș, Diana M., Marcu, Loredana G., Virag, Vasile, Virag, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375603/
https://www.ncbi.nlm.nih.gov/pubmed/37507741
http://dx.doi.org/10.1186/s13014-023-02313-5
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author Ghemiș, Diana M.
Marcu, Loredana G.
Virag, Vasile
Virag, Adriana
author_facet Ghemiș, Diana M.
Marcu, Loredana G.
Virag, Vasile
Virag, Adriana
author_sort Ghemiș, Diana M.
collection PubMed
description BACKGROUND: Beam matching is a concept in radiotherapy applied to clinics where more than one linac is employed to harmonise beam characteristics across linacs for allowing patients interchange without replanning. In view of this, the current study analyzes and compares dosimetric characteristics of 6MV flattening filter free and flattened beams of three beam-matched linear accelerators (linacs) from three different clinics with the aim to evaluate the matching under tight criteria for gamma analysis. METHODS: Three Elekta linacs from three different clinics were included. The linacs have the same collimator assembly, Elekta Agility. Beam data were collected during commissioning process using PTW dosimetry systems. Dose profiles and percentage depth doses (PDD) were analyzed using 1D gamma analysis (1 mm/1%) as well as the following parameters: depth of maximum dose, PDD10, flatness, unflattnes, symmetry, penumbra, output factors. Additionally, five stereotactic treatment plans were optimized in one clinic and calculated by all three planning systems (Monaco) for a dosimetric comparison. RESULTS: Gamma analysis of dose profiles and PDDs showed clinically acceptable results of 96.3% passing rate for profiles and 100% passing rate for PDDs. All dosimetric parameters were in good agreement with the reference data. Furthermore, dosimetric comparisons between stereotactic treatment plans showed a maximum standard deviation of 0.48 Gy for the maximum dose to PTV, and a maximum standard deviation of 0.1 Gy for the dose to the organs at risk. CONCLUSIONS: All three linacs showed a strong agreement between parameters and passed the gamma analysis using 1% DD/1mm DTA criteria. This study confirmed the matching between linacs, offering the possibility to interchange patients with no replanning.
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spelling pubmed-103756032023-07-29 Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam-matched linacs: a three-institutional study Ghemiș, Diana M. Marcu, Loredana G. Virag, Vasile Virag, Adriana Radiat Oncol Research BACKGROUND: Beam matching is a concept in radiotherapy applied to clinics where more than one linac is employed to harmonise beam characteristics across linacs for allowing patients interchange without replanning. In view of this, the current study analyzes and compares dosimetric characteristics of 6MV flattening filter free and flattened beams of three beam-matched linear accelerators (linacs) from three different clinics with the aim to evaluate the matching under tight criteria for gamma analysis. METHODS: Three Elekta linacs from three different clinics were included. The linacs have the same collimator assembly, Elekta Agility. Beam data were collected during commissioning process using PTW dosimetry systems. Dose profiles and percentage depth doses (PDD) were analyzed using 1D gamma analysis (1 mm/1%) as well as the following parameters: depth of maximum dose, PDD10, flatness, unflattnes, symmetry, penumbra, output factors. Additionally, five stereotactic treatment plans were optimized in one clinic and calculated by all three planning systems (Monaco) for a dosimetric comparison. RESULTS: Gamma analysis of dose profiles and PDDs showed clinically acceptable results of 96.3% passing rate for profiles and 100% passing rate for PDDs. All dosimetric parameters were in good agreement with the reference data. Furthermore, dosimetric comparisons between stereotactic treatment plans showed a maximum standard deviation of 0.48 Gy for the maximum dose to PTV, and a maximum standard deviation of 0.1 Gy for the dose to the organs at risk. CONCLUSIONS: All three linacs showed a strong agreement between parameters and passed the gamma analysis using 1% DD/1mm DTA criteria. This study confirmed the matching between linacs, offering the possibility to interchange patients with no replanning. BioMed Central 2023-07-28 /pmc/articles/PMC10375603/ /pubmed/37507741 http://dx.doi.org/10.1186/s13014-023-02313-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Ghemiș, Diana M.
Marcu, Loredana G.
Virag, Vasile
Virag, Adriana
Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam-matched linacs: a three-institutional study
title Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam-matched linacs: a three-institutional study
title_full Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam-matched linacs: a three-institutional study
title_fullStr Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam-matched linacs: a three-institutional study
title_full_unstemmed Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam-matched linacs: a three-institutional study
title_short Dosimetric characteristics of 6MV flattening filter free and flattened beams among beam-matched linacs: a three-institutional study
title_sort dosimetric characteristics of 6mv flattening filter free and flattened beams among beam-matched linacs: a three-institutional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375603/
https://www.ncbi.nlm.nih.gov/pubmed/37507741
http://dx.doi.org/10.1186/s13014-023-02313-5
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