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Inequalities in the burden of non-communicable diseases across European countries: a systematic analysis of the Global Burden of Disease 2019 study

BACKGROUND: Although overall health status in the last decades improved, health inequalities due to non-communicable diseases (NCDs) persist between and within European countries. There is a lack of studies giving insights into health inequalities related to NCDs in the European Economic Area (EEA)...

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Autores principales: Andrade, Carlos Alexandre Soares, Mahrouseh, Nour, Gabrani, Jonila, Charalampous, Periklis, Cuschieri, Sarah, Grad, Diana Alecsandra, Unim, Brigid, Mechili, Enkeleint A., Chen-Xu, José, Devleesschauwer, Brecht, Isola, Gaetano, von der Lippe, Elena, Baravelli, Carl Michael, Fischer, Florian, Weye, Nanna, Balaj, Mirza, Haneef, Romana, Economou, Mary, Haagsma, Juanita A., Varga, Orsolya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375608/
https://www.ncbi.nlm.nih.gov/pubmed/37507733
http://dx.doi.org/10.1186/s12939-023-01958-8
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author Andrade, Carlos Alexandre Soares
Mahrouseh, Nour
Gabrani, Jonila
Charalampous, Periklis
Cuschieri, Sarah
Grad, Diana Alecsandra
Unim, Brigid
Mechili, Enkeleint A.
Chen-Xu, José
Devleesschauwer, Brecht
Isola, Gaetano
von der Lippe, Elena
Baravelli, Carl Michael
Fischer, Florian
Weye, Nanna
Balaj, Mirza
Haneef, Romana
Economou, Mary
Haagsma, Juanita A.
Varga, Orsolya
author_facet Andrade, Carlos Alexandre Soares
Mahrouseh, Nour
Gabrani, Jonila
Charalampous, Periklis
Cuschieri, Sarah
Grad, Diana Alecsandra
Unim, Brigid
Mechili, Enkeleint A.
Chen-Xu, José
Devleesschauwer, Brecht
Isola, Gaetano
von der Lippe, Elena
Baravelli, Carl Michael
Fischer, Florian
Weye, Nanna
Balaj, Mirza
Haneef, Romana
Economou, Mary
Haagsma, Juanita A.
Varga, Orsolya
author_sort Andrade, Carlos Alexandre Soares
collection PubMed
description BACKGROUND: Although overall health status in the last decades improved, health inequalities due to non-communicable diseases (NCDs) persist between and within European countries. There is a lack of studies giving insights into health inequalities related to NCDs in the European Economic Area (EEA) countries. Therefore, the aim of the present study was to quantify health inequalities in age-standardized disability adjusted life years (DALY) rates for NCDs overall and 12 specific NCDs across 30 EEA countries between 1990 and 2019. Also, this study aimed to determine trends in health inequalities and to identify those NCDs where the inequalities were the highest. METHODS: DALY rate ratios were calculated to determine and compare inequalities between the 30 EEA countries, by sex, and across time. Annual rate of change was used to determine the differences in DALY rate between 1990 and 2019 for males and females. The Gini Coefficient (GC) was used to measure the DALY rate inequalities across countries, and the Slope Index of Inequality (SII) to estimate the average absolute difference in DALY rate across countries. RESULTS: Between 1990 and 2019, there was an overall declining trend in DALY rate, with larger declines among females compared to males. Among EEA countries, in 2019 the highest NCD DALY rate for both sexes were observed for Bulgaria. For the whole period, the highest DALY rate ratios were identified for digestive diseases, diabetes and kidney diseases, substance use disorders, cardiovascular diseases (CVD), and chronic respiratory diseases – representing the highest inequality between countries. In 2019, the highest DALY rate ratio was found between Bulgaria and Iceland for males. GC and SII indicated that the highest inequalities were due to CVD for most of the study period – however, overall levels of inequality were low. CONCLUSIONS: The inequality in level 1 NCDs DALYs rate is relatively low among all the countries. CVDs, digestive diseases, diabetes and kidney diseases, substance use disorders, and chronic respiratory diseases are the NCDs that exhibit higher levels of inequality across countries in the EEA. This might be mitigated by applying tailored preventive measures and enabling healthcare access. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12939-023-01958-8.
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spelling pubmed-103756082023-07-29 Inequalities in the burden of non-communicable diseases across European countries: a systematic analysis of the Global Burden of Disease 2019 study Andrade, Carlos Alexandre Soares Mahrouseh, Nour Gabrani, Jonila Charalampous, Periklis Cuschieri, Sarah Grad, Diana Alecsandra Unim, Brigid Mechili, Enkeleint A. Chen-Xu, José Devleesschauwer, Brecht Isola, Gaetano von der Lippe, Elena Baravelli, Carl Michael Fischer, Florian Weye, Nanna Balaj, Mirza Haneef, Romana Economou, Mary Haagsma, Juanita A. Varga, Orsolya Int J Equity Health Research BACKGROUND: Although overall health status in the last decades improved, health inequalities due to non-communicable diseases (NCDs) persist between and within European countries. There is a lack of studies giving insights into health inequalities related to NCDs in the European Economic Area (EEA) countries. Therefore, the aim of the present study was to quantify health inequalities in age-standardized disability adjusted life years (DALY) rates for NCDs overall and 12 specific NCDs across 30 EEA countries between 1990 and 2019. Also, this study aimed to determine trends in health inequalities and to identify those NCDs where the inequalities were the highest. METHODS: DALY rate ratios were calculated to determine and compare inequalities between the 30 EEA countries, by sex, and across time. Annual rate of change was used to determine the differences in DALY rate between 1990 and 2019 for males and females. The Gini Coefficient (GC) was used to measure the DALY rate inequalities across countries, and the Slope Index of Inequality (SII) to estimate the average absolute difference in DALY rate across countries. RESULTS: Between 1990 and 2019, there was an overall declining trend in DALY rate, with larger declines among females compared to males. Among EEA countries, in 2019 the highest NCD DALY rate for both sexes were observed for Bulgaria. For the whole period, the highest DALY rate ratios were identified for digestive diseases, diabetes and kidney diseases, substance use disorders, cardiovascular diseases (CVD), and chronic respiratory diseases – representing the highest inequality between countries. In 2019, the highest DALY rate ratio was found between Bulgaria and Iceland for males. GC and SII indicated that the highest inequalities were due to CVD for most of the study period – however, overall levels of inequality were low. CONCLUSIONS: The inequality in level 1 NCDs DALYs rate is relatively low among all the countries. CVDs, digestive diseases, diabetes and kidney diseases, substance use disorders, and chronic respiratory diseases are the NCDs that exhibit higher levels of inequality across countries in the EEA. This might be mitigated by applying tailored preventive measures and enabling healthcare access. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12939-023-01958-8. BioMed Central 2023-07-28 /pmc/articles/PMC10375608/ /pubmed/37507733 http://dx.doi.org/10.1186/s12939-023-01958-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Andrade, Carlos Alexandre Soares
Mahrouseh, Nour
Gabrani, Jonila
Charalampous, Periklis
Cuschieri, Sarah
Grad, Diana Alecsandra
Unim, Brigid
Mechili, Enkeleint A.
Chen-Xu, José
Devleesschauwer, Brecht
Isola, Gaetano
von der Lippe, Elena
Baravelli, Carl Michael
Fischer, Florian
Weye, Nanna
Balaj, Mirza
Haneef, Romana
Economou, Mary
Haagsma, Juanita A.
Varga, Orsolya
Inequalities in the burden of non-communicable diseases across European countries: a systematic analysis of the Global Burden of Disease 2019 study
title Inequalities in the burden of non-communicable diseases across European countries: a systematic analysis of the Global Burden of Disease 2019 study
title_full Inequalities in the burden of non-communicable diseases across European countries: a systematic analysis of the Global Burden of Disease 2019 study
title_fullStr Inequalities in the burden of non-communicable diseases across European countries: a systematic analysis of the Global Burden of Disease 2019 study
title_full_unstemmed Inequalities in the burden of non-communicable diseases across European countries: a systematic analysis of the Global Burden of Disease 2019 study
title_short Inequalities in the burden of non-communicable diseases across European countries: a systematic analysis of the Global Burden of Disease 2019 study
title_sort inequalities in the burden of non-communicable diseases across european countries: a systematic analysis of the global burden of disease 2019 study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375608/
https://www.ncbi.nlm.nih.gov/pubmed/37507733
http://dx.doi.org/10.1186/s12939-023-01958-8
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