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A brain cytokine-independent switch in cortical activity marks the onset of sickness behavior triggered by acute peripheral inflammation

Systemic inflammation triggers protective as well as pro-inflammatory responses in the brain based on neuronal and/or cytokine signaling, and it associates with acutely and protractedly disrupted cognition. However, the multiple mechanisms underlying the peripheral–central inflammatory signaling are...

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Detalles Bibliográficos
Autores principales: Kurki, Samu N., Ala-Kurikka, Tommi, Lipponen, Arto, Pospelov, Alexey S., Rolova, Taisia, Koistinaho, Jari, Voipio, Juha, Kaila, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375675/
https://www.ncbi.nlm.nih.gov/pubmed/37507711
http://dx.doi.org/10.1186/s12974-023-02851-5