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Characterization of 3D heterocellular spheroids of pancreatic ductal adenocarcinoma for the study of cell interactions in the tumor immune microenvironment

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies nowadays. The available chemo- and immunotherapies are often ineffective in treating PDAC due to its immunosuppressive and highly desmoplastic tumor immune microenvironment (TIME), which is hardly reproduced in the existing...

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Detalles Bibliográficos
Autores principales: Giustarini, Giulio, Teng, Germaine, Pavesi, Andrea, Adriani, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375712/
https://www.ncbi.nlm.nih.gov/pubmed/37519820
http://dx.doi.org/10.3389/fonc.2023.1156769