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PPARγ-dependent hepatic macrophage switching acts as a central hub for hUCMSC-mediated alleviation of decompensated liver cirrhosis in rats

BACKGROUND: Decompensated liver cirrhosis (DLC), a terminal-stage complication of liver disease, is a major cause of morbidity and mortality in patients with hepatopathies. Human umbilical cord mesenchymal stem cell (hUCMSC) therapy has emerged as a novel treatment alternative for the treatment of D...

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Detalles Bibliográficos
Autores principales: Yao, Yunqi, Zhang, Lin, Cheng, Fuyi, Jiang, Qingyuan, Ye, Yixin, Ren, Yushuang, He, Yuting, Su, Dongsheng, Cheng, Lin, Shi, Gang, Dai, Lei, Deng, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375757/
https://www.ncbi.nlm.nih.gov/pubmed/37501214
http://dx.doi.org/10.1186/s13287-023-03416-2