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PPARγ-dependent hepatic macrophage switching acts as a central hub for hUCMSC-mediated alleviation of decompensated liver cirrhosis in rats
BACKGROUND: Decompensated liver cirrhosis (DLC), a terminal-stage complication of liver disease, is a major cause of morbidity and mortality in patients with hepatopathies. Human umbilical cord mesenchymal stem cell (hUCMSC) therapy has emerged as a novel treatment alternative for the treatment of D...
Autores principales: | Yao, Yunqi, Zhang, Lin, Cheng, Fuyi, Jiang, Qingyuan, Ye, Yixin, Ren, Yushuang, He, Yuting, Su, Dongsheng, Cheng, Lin, Shi, Gang, Dai, Lei, Deng, Hongxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375757/ https://www.ncbi.nlm.nih.gov/pubmed/37501214 http://dx.doi.org/10.1186/s13287-023-03416-2 |
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