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Metabolic systems approaches update molecular insights of clinical phenotypes and cardiovascular risk in patients with homozygous familial hypercholesterolemia

BACKGROUND: Homozygous familial hypercholesterolemia (HoFH) is an orphan metabolic disease characterized by extremely elevated low-density lipoprotein cholesterol (LDL-C), xanthomas, aortic stenosis, and premature atherosclerotic cardiovascular disease (ASCVD). In addition to LDL-C, studies in exper...

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Detalles Bibliográficos
Autores principales:	Du, Zhiyong, Li, Fan, Jiang, Long, Li, Linyi, Du, Yunhui, Yu, Huahui, Luo, Yan, Wang, Yu, Sun, Haili, Hu, Chaowei, Li, Jianping, Yang, Ya, Jiao, Xiaolu, Wang, Luya, Qin, Yanwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375787/ https://www.ncbi.nlm.nih.gov/pubmed/37501168 http://dx.doi.org/10.1186/s12916-023-02967-8

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