PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand

[Image: see text] Although leprosy (Hansen’s disease) is one of the oldest known diseases, the pathogenicity of Mycobacterium leprae (M. leprae) remains enigmatic. Indeed, the cell wall components responsible for the immune response against M. leprae are as yet largely unidentified. We reveal here p...

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Detalles Bibliográficos
Autores principales: Ishizuka, Shigenari, van Dijk, J. Hessel M., Kawakita, Tomomi, Miyamoto, Yuji, Maeda, Yumi, Goto, Masamichi, Le Calvez, Guillaume, Groot, L. Melanie, Witte, Martin D., Minnaard, Adriaan J., van der Marel, Gijsbert A., Ato, Manabu, Nagae, Masamichi, Codée, Jeroen D. C., Yamasaki, Sho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375886/
https://www.ncbi.nlm.nih.gov/pubmed/37521780
http://dx.doi.org/10.1021/acscentsci.3c00040

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