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Mechanisms of Piperacillin/Tazobactam Nephrotoxicity: Piperacillin/Tazobactam-Induced Direct Tubular Damage in Mice

Piperacillin/tazobactam (PT) is one of the most commonly prescribed antibiotics for critically ill patients in intensive care. PT has been reported to cause direct nephrotoxicity; however, the underlying mechanisms remain unknown. We investigated the mechanisms underlying PT nephrotoxicity using a m...

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Detalles Bibliográficos
Autores principales: Yang, Jihyun, Ko, Yoon Sook, Lee, Hee Young, Fang, Yina, Oh, Se Won, Kim, Myung-Gyu, Cho, Won Yong, Jo, Sang-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376029/
https://www.ncbi.nlm.nih.gov/pubmed/37508217
http://dx.doi.org/10.3390/antibiotics12071121