Cargando…

N(6)-Methyladenosine Directly Regulates CD40L Expression in CD4(+) T Lymphocytes

SIMPLE SUMMARY: The tight regulation of the expression of cytokines, surface receptors and co-stimulatory and co-inhibitory molecules is necessary for a well-functioning immune system. There are various cellular processes that regulate the expression of these immune regulatory proteins, for instance...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Vroonhoven, Ellen C. N., Picavet, Lucas W., Scholman, Rianne C., van den Dungen, Noortje A. M., Mokry, Michal, Evers, Anouk, Lebbink, Robert J., Calis, Jorg J. A., Vastert, Sebastiaan J., van Loosdregt, Jorg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376055/ https://www.ncbi.nlm.nih.gov/pubmed/37508433 http://dx.doi.org/10.3390/biology12071004

Ejemplares similares

Epigenetic changes in inflammatory arthritis monocytes contribute to disease and can be targeted by JAK inhibition
por: Peeters, Janneke G C, et al.
Publicado: (2023)

Review: Enhancers in Autoimmune Arthritis: Implications and Therapeutic Potential
por: Peeters, Janneke G. C., et al.
Publicado: (2017)

Restoring T Cell Tolerance, Exploring the Potential of Histone Deacetylase Inhibitors for the Treatment of Juvenile Idiopathic Arthritis
por: Nijhuis, Lotte, et al.
Publicado: (2019)

Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation
por: Mijnheer, Gerdien, et al.
Publicado: (2021)

Tissue–Resident Memory T Cells in Chronic Inflammation—Local Cells with Systemic Effects?
por: Samat, Anoushka Ashok Kumar, et al.
Publicado: (2021)

Autoimmune disease-associated gene expression is reduced by BET-inhibition
por: Peeters, Janneke G.C., et al.
Publicado: (2015)

Conventional dendritic cells type 1 are strongly enriched, quiescent and relatively tolerogenic in local inflammatory arthritis
por: Boltjes, Arjan, et al.
Publicado: (2023)

Human regulatory T cells locally differentiate and are functionally heterogeneous within the inflamed arthritic joint
por: Lutter, Lisanne, et al.
Publicado: (2022)

High sensitivity of cancer exome-based CD8 T cell neo-antigen identification
por: van Buuren, Marit M, et al.
Publicado: (2014)

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagy
por: Peeters, J.G.C., et al.
Publicado: (2018)

The CD40–CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis
por: Aarts, Suzanne A. B. M., et al.
Publicado: (2017)

Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis
por: Teruel, María, et al.
Publicado: (2012)

Induction of cytotoxic effector cells towards cholangiocellular, pancreatic, and colorectal tumor cells by activation of the immune checkpoint CD40/CD40L on dendritic cells
por: Sadeghlar, Farsaneh, et al.
Publicado: (2020)

The clinical and experimental treatment of Juvenile Idiopathic Arthritis
por: Nijhuis, L, et al.
Publicado: (2023)

CD40–CD40L in Neurological Disease
por: Ots, Heather D., et al.
Publicado: (2022)

Human Tregs at the materno-fetal interface show site-specific adaptation reminiscent of tumor Tregs
por: Wienke, Judith, et al.
Publicado: (2020)

The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease
por: Bosmans, Laura A., et al.
Publicado: (2020)

A circulating reservoir of pathogenic-like CD4(+) T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment
por: Spreafico, Roberto, et al.
Publicado: (2016)

IL-18 production upon s100 stimulation is reduced in active sJIA patients compared to sJIA patients in remission and healthy controls
por: Haar, Nienke Ter, et al.
Publicado: (2014)

Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
por: Lacy, Michael, et al.
Publicado: (2021)

Chronic Immune Activation in HIV-1 Infection Contributes to Reduced Interferon Alpha Production via Enhanced CD40:CD40 Ligand Interaction
por: Donhauser, Norbert, et al.
Publicado: (2012)

Downregulation of CD40L–CD40 attenuates seizure susceptibility and severity of seizures
por: Pototskiy, Esther, et al.
Publicado: (2021)

NRF2/Itaconate Axis Regulates Metabolism and Inflammatory Properties of T Cells in Children with JIA
por: Rajendiran, Anandhi, et al.
Publicado: (2022)

Adipocytes in their (CD)40s
por: Bertola, Adeline, et al.
Publicado: (2023)

CD40 in coronary artery disease: a matter of macrophages?
por: Jansen, Matthijs F., et al.
Publicado: (2016)

CD40-CD40L Interaction in Immunity Against Protozoan Infections
por: Chamekh, Mustapha
Publicado: (2007)

The Role of CD40/CD40 Ligand Interactions in Bone Marrow Granulopoiesis
por: Mavroudi, Irene, et al.
Publicado: (2011)

CD40/CD40 LIGAND INTERACTIONS IN IMMUNE RESPONSES AND PULMONARY IMMUNITY
por: KAWABE, TSUTOMU, et al.
Publicado: (2011)

Platelets as Key Factors in Inflammation: Focus on CD40L/CD40
por: Cognasse, Fabrice, et al.
Publicado: (2022)

Levels of human platelet-derived soluble CD40 ligand depend on haplotypes of CD40LG-CD40-ITGA2
por: Aloui, Chaker, et al.
Publicado: (2016)

Macrophages and Fc-receptor interactions contribute to the antitumour activities of the anti-CD40 antibody SGN-40
por: Oflazoglu, E, et al.
Publicado: (2009)

Precision Medicine in Graves’ Disease: CD40 Gene Variants Predict Clinical Response to an Anti-CD40 Monoclonal Antibody
por: Faustino, Larissa C., et al.
Publicado: (2021)

The Contribution of CD40/CD40L Axis in Inflammatory Bowel Disease: An Update
por: Senhaji, Nezha, et al.
Publicado: (2015)

CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation
por: Elmetwali, Taha, et al.
Publicado: (2020)

CD40/CD40L expression and its prognostic value in cervical cancer
por: Grazia, G.A., et al.
Publicado: (2023)

Author Correction: Downregulation of CD40L–CD40 attenuates seizure susceptibility and severity of seizures
por: Pototskiy, Esther, et al.
Publicado: (2021)

RNA aptamers with specific binding affinity to CD40 (CD40Apt) represents a promising antagonist of the CD40-CD40L signaling for thyroid-associated ophthalmopathy (TAO) treatment in mouse
por: Chen, Yizhi, et al.
Publicado: (2023)

Adipocytes control hematopoiesis and inflammation through CD40 signaling
por: Reiche, Myrthe E., et al.
Publicado: (2022)

Inhibition of complement activation by CD55 overexpression in human induced pluripotent stem cell derived kidney organoids
por: Gaykema, Lonneke H., et al.
Publicado: (2023)

A Critical Role for Cd40–Cd40 Ligand Interactions in Amplification of the Mucosal Cd8 T Cell Response
por: Lefrançois, Leo, et al.
Publicado: (1999)

Cannot write session to /tmp/vufind_sessions/sess_f6kq79kj4faelq3kmncciviqib