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Optimization of DIC-Tripolium Ecofriendly Extraction Process: Recovery of Hesperidin from Orange Byproducts, Antioxidant and α-Amylase Inhibition of Extracts

This study aimed to investigate the effect of an innovative ecofriendly process—instant controlled pressure drop technology, also known as “détente instantanée contrôlée” or DIC—coupled with Tripolium extraction (DIC-Tripolium), on the hesperidin recovery, and antioxidant and antidiabetic activities...

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Autores principales: Ben Abdallah, Mariem, Chadni, Morad, M’hiri, Nouha, Brunissen, Fanny, Rokbeni, Nesrine, Ioannou, Irina, Allaf, Karim, Besombes, Colette, Boudhrioua, Nourhene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376484/
https://www.ncbi.nlm.nih.gov/pubmed/37507886
http://dx.doi.org/10.3390/antiox12071346
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author Ben Abdallah, Mariem
Chadni, Morad
M’hiri, Nouha
Brunissen, Fanny
Rokbeni, Nesrine
Ioannou, Irina
Allaf, Karim
Besombes, Colette
Boudhrioua, Nourhene
author_facet Ben Abdallah, Mariem
Chadni, Morad
M’hiri, Nouha
Brunissen, Fanny
Rokbeni, Nesrine
Ioannou, Irina
Allaf, Karim
Besombes, Colette
Boudhrioua, Nourhene
author_sort Ben Abdallah, Mariem
collection PubMed
description This study aimed to investigate the effect of an innovative ecofriendly process—instant controlled pressure drop technology, also known as “détente instantanée contrôlée” or DIC—coupled with Tripolium extraction (DIC-Tripolium), on the hesperidin recovery, and antioxidant and antidiabetic activities of orange byproduct extracts. A DIC pretreatment was applied to partially dried orange byproducts (~16% wet basis). A central composite rotatable design (CCRD), composed of 13 experimental trials (four factorial points, four-star points, and five repetitions for the central point), was followed by a Tripolium process consisting of successive intermittent extraction periods using ethanol/water solvent at 20 ± 1 °C, 5 kPa for 5 min and m/v ratio = 5 g/50 mL. The DIC pretreatment, coupled with the Tripolium process, increased the extractability of hesperidin (from 1.55- to 4.67-fold compared to untreated DIC orange byproducts). The radical scavenging activities of the extracts were also enhanced or preserved in different DIC–Tripolium extracts. The α-Amylase inhibition percentage varied between 55.6 ± 0.02 and 88.30 ± 0.01% according to DIC–Tripolium conditions. The multi-criteria optimized condition of DIC–Tripolium extraction, allowing for the maximization of the hesperidin content, radical scavenging activities, iron chelating activity, and α-amylase inhibition of extracts, corresponds to a DIC saturated steam pressure of 599.4 kPa and a DIC pretreatment time of 38 s.
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spelling pubmed-103764842023-07-29 Optimization of DIC-Tripolium Ecofriendly Extraction Process: Recovery of Hesperidin from Orange Byproducts, Antioxidant and α-Amylase Inhibition of Extracts Ben Abdallah, Mariem Chadni, Morad M’hiri, Nouha Brunissen, Fanny Rokbeni, Nesrine Ioannou, Irina Allaf, Karim Besombes, Colette Boudhrioua, Nourhene Antioxidants (Basel) Article This study aimed to investigate the effect of an innovative ecofriendly process—instant controlled pressure drop technology, also known as “détente instantanée contrôlée” or DIC—coupled with Tripolium extraction (DIC-Tripolium), on the hesperidin recovery, and antioxidant and antidiabetic activities of orange byproduct extracts. A DIC pretreatment was applied to partially dried orange byproducts (~16% wet basis). A central composite rotatable design (CCRD), composed of 13 experimental trials (four factorial points, four-star points, and five repetitions for the central point), was followed by a Tripolium process consisting of successive intermittent extraction periods using ethanol/water solvent at 20 ± 1 °C, 5 kPa for 5 min and m/v ratio = 5 g/50 mL. The DIC pretreatment, coupled with the Tripolium process, increased the extractability of hesperidin (from 1.55- to 4.67-fold compared to untreated DIC orange byproducts). The radical scavenging activities of the extracts were also enhanced or preserved in different DIC–Tripolium extracts. The α-Amylase inhibition percentage varied between 55.6 ± 0.02 and 88.30 ± 0.01% according to DIC–Tripolium conditions. The multi-criteria optimized condition of DIC–Tripolium extraction, allowing for the maximization of the hesperidin content, radical scavenging activities, iron chelating activity, and α-amylase inhibition of extracts, corresponds to a DIC saturated steam pressure of 599.4 kPa and a DIC pretreatment time of 38 s. MDPI 2023-06-27 /pmc/articles/PMC10376484/ /pubmed/37507886 http://dx.doi.org/10.3390/antiox12071346 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ben Abdallah, Mariem
Chadni, Morad
M’hiri, Nouha
Brunissen, Fanny
Rokbeni, Nesrine
Ioannou, Irina
Allaf, Karim
Besombes, Colette
Boudhrioua, Nourhene
Optimization of DIC-Tripolium Ecofriendly Extraction Process: Recovery of Hesperidin from Orange Byproducts, Antioxidant and α-Amylase Inhibition of Extracts
title Optimization of DIC-Tripolium Ecofriendly Extraction Process: Recovery of Hesperidin from Orange Byproducts, Antioxidant and α-Amylase Inhibition of Extracts
title_full Optimization of DIC-Tripolium Ecofriendly Extraction Process: Recovery of Hesperidin from Orange Byproducts, Antioxidant and α-Amylase Inhibition of Extracts
title_fullStr Optimization of DIC-Tripolium Ecofriendly Extraction Process: Recovery of Hesperidin from Orange Byproducts, Antioxidant and α-Amylase Inhibition of Extracts
title_full_unstemmed Optimization of DIC-Tripolium Ecofriendly Extraction Process: Recovery of Hesperidin from Orange Byproducts, Antioxidant and α-Amylase Inhibition of Extracts
title_short Optimization of DIC-Tripolium Ecofriendly Extraction Process: Recovery of Hesperidin from Orange Byproducts, Antioxidant and α-Amylase Inhibition of Extracts
title_sort optimization of dic-tripolium ecofriendly extraction process: recovery of hesperidin from orange byproducts, antioxidant and α-amylase inhibition of extracts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376484/
https://www.ncbi.nlm.nih.gov/pubmed/37507886
http://dx.doi.org/10.3390/antiox12071346
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