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Gene Expression and Drug Sensitivity Analysis of Mitochondrial Chaperones Reveals That HSPD1 and TRAP1 Expression Correlates with Sensitivity to Inhibitors of DNA Replication and Mitosis

SIMPLE SUMMARY: Mitochondria—the energy-producing organelles of a cell—contain numerous enzymes essential for many cellular processes. Enzymes, which are imported into the mitochondria in linear form, must be properly folded to become functional. It is known that the folding is facilitated by molecu...

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Detalles Bibliográficos
Autores principales: Badarni, Mai, Gabbay, Shani, Elkabets, Moshe, Rotblat, Barak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376793/
https://www.ncbi.nlm.nih.gov/pubmed/37508418
http://dx.doi.org/10.3390/biology12070988