The TP53 Codon 72 Arginine Polymorphism Is Found with Increased TP53 Somatic Mutations in HPV(−) and in an Increased Percentage among HPV(+) Norwegian HNSCC Patients

Background: Somatic TP53 mutations are frequent in head and neck squamous cell carcinoma (HNSCC) and are important pathogenic factors. Objective: To study TP53 mutations relative to the presence of human papillomavirus (HPV) in tumors in HNSCC patients. Methods: Using a custom-made next-generation s...

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Detalles Bibliográficos
Autores principales: Moe, Svein Erik, Erland, Fredrik A., Fromreide, Siren, Lybak, Stein, Brydoy, Marianne, Dongre, Harsh N., Dhayalan, Sophia M., Costea, Daniela-Elena, Vintermyr, Olav K., Aarstad, Hans Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376802/
https://www.ncbi.nlm.nih.gov/pubmed/37509476
http://dx.doi.org/10.3390/biomedicines11071838

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