Cargando…

Sex-Linked Growth Disorder and Aberrant Pituitary Gene Expression in Nestin-Cre-Mediated Egr1 Conditional Knockout Mice

SIMPLE SUMMARY: Reduced growth hormone levels were observed in mice without the Egr1 gene and mice carrying a Nestin-Cre driver. It remains unknown why these two strains of mice share a similar phenotype and whether the dysregulation of hormone production in the pituitary occurs via the same mechani...

Descripción completa

Detalles Bibliográficos
Autores principales:	Swilley, Cody, Lin, Yu, Zheng, Yuze, Xu, Xiguang, Liu, Min, Zimmerman, Kurt, Xie, Hehuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376842/ https://www.ncbi.nlm.nih.gov/pubmed/37508396 http://dx.doi.org/10.3390/biology12070966

Ejemplares similares

Sex linked behavioral and hippocampal transcriptomic changes in mice with cell-type specific Egr1 loss
por: Swilley, Cody, et al.
Publicado: (2023)

Aberrant glial activation and synaptic defects in CaMKIIα-iCre and nestin-Cre transgenic mouse models
por: Alia, Alia O., et al.
Publicado: (2022)

Nestin-Cre Mice Are Affected by Hypopituitarism, Which Is Not Due to Significant Activity of the Transgene in the Pituitary Gland
por: Galichet, Christophe, et al.
Publicado: (2010)

Germ-Line Recombination Activity of the Widely Used hGFAP-Cre and Nestin-Cre Transgenes
por: Zhang, Jiong, et al.
Publicado: (2013)

EGR2 is elevated and positively regulates inflammatory IFNγ production in lupus CD4(+) T cells
por: Dai, Rujuan, et al.
Publicado: (2020)

A Nestin-cre transgenic mouse is insufficient for recombination in early embryonic neural progenitors
por: Liang, Huixuan, et al.
Publicado: (2012)

Egr2::Cre Mediated Conditional Ablation of Dicer Disrupts Histogenesis of Mammalian Central Auditory Nuclei
por: Rosengauer, Elena, et al.
Publicado: (2012)

Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone
por: Declercq, Jeroen, et al.
Publicado: (2015)

A Conditional Knockout Toolkit for Caenorhabditis elegans Based on the Cre/loxP Recombination
por: Kage-Nakadai, Eriko, et al.
Publicado: (2014)

Utility of progesterone receptor‐ires‐Cre to generate conditional knockout mice for uterine study
por: Namiki, Takafumi, et al.
Publicado: (2021)

Microarray analysis of retinal gene expression in Egr-1 knockout mice
por: Schippert, Ruth, et al.
Publicado: (2009)

Amhr2-Cre–Mediated Global Tspo Knockout
por: Fan, Jinjiang, et al.
Publicado: (2020)

Influence of Phosphodiesterase Inhibition on CRE- and EGR1-Dependent Transcription in a Mouse Hippocampal Cell Line
por: Maronde, Erik
Publicado: (2020)

EGR1 recruits TET1 to shape the brain methylome during development and upon neuronal activity
por: Sun, Zhixiong, et al.
Publicado: (2019)

Conditional Transgenesis Using Dimerizable Cre (DiCre)
por: Jullien, Nicolas, et al.
Publicado: (2007)

Somatostatin-IRES-Cre Mice: Between Knockout and Wild-Type?
por: Viollet, Cécile, et al.
Publicado: (2017)

Commentary: Amhr2-Cre-Mediated Global Tspo Knockout
por: Selvaraj, Vimal, et al.
Publicado: (2020)

Expression and clinical significance of EGR-1 and PTEN in the pituitary tumors of elderly patients
por: Sun, Shu-Wen, et al.
Publicado: (2017)

Sex-specific effects of Cre expression in Syn1Cre mice
por: Baghdadi, Maarouf, et al.
Publicado: (2023)

Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines
por: Veselska, Renata, et al.
Publicado: (2008)

The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development
por: Thomson, Ella, et al.
Publicado: (2021)

Neuronal Depolarization Induced RNA m(5)C Methylation Changes in Mouse Cortical Neurons
por: Xu, Xiguang, et al.
Publicado: (2022)

Unspecific DNA recombination in AdipoqCre-ER(T2) – mediated knockout approaches in transgenic mice is sex-, age- and genotype-dependent
por: Lindhorst, Andreas, et al.
Publicado: (2019)

The expression of B23 and EGR1 proteins is functionally linked in tumor cells under stress conditions
por: Ponti, Donatella, et al.
Publicado: (2015)

Emerging biomarker in carcinogenesis. Focus on Nestin
por: Nowogrodzka, Katarzyna, et al.
Publicado: (2022)

GFAP-Cre-Mediated Transgenic Activation of Bmi1 Results in Pituitary Tumors
por: Westerman, Bart A., et al.
Publicado: (2012)

Molecular imaging of nestin in neuroinflammatory conditions reveals marked signal induction in activated microglia
por: Krishnasamy, Senthil, et al.
Publicado: (2017)

Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreER(T2)/Diphtheria Toxin Fragment A Transgenic Mice
por: Yun, Sanghee, et al.
Publicado: (2016)

CreZOO—the European virtual repository of Cre and other targeted conditional driver strains
por: Chandras, Christina, et al.
Publicado: (2012)

Systematic evaluation of parameters in RNA bisulfite sequencing data generation and analysis
por: Johnson, Zachary, et al.
Publicado: (2022)

Dynamics of RNA m(5)C modification during brain development
por: Johnson, Zachary, et al.
Publicado: (2023)

Cell Type-specific Knockout with Gli1-mediated Cre Recombination in the Developing Cerebellum
por: Choi, Jung-Mi, et al.
Publicado: (2021)

The Missing Link: Cre Pigs for Cancer Research
por: Kalla, Daniela, et al.
Publicado: (2021)

Different Cre systems induce differential microRNA landscapes and abnormalities in the female reproductive tracts of Dgcr8 conditional knockout mice
por: Kim, Yeon Sun, et al.
Publicado: (2021)

Egr2 and Egr3 are the unique regulators for systemic autoimmunity
por: Sumitomo, Shuji, et al.
Publicado: (2013)

Production of Monoclonal Antibody against Human Nestin
por: Hadavi, Reza, et al.
Publicado: (2010)

Nestin as a marker of cancer stem cells
por: Neradil, Jakub, et al.
Publicado: (2015)

Nestin contributes to laser choroidal and retinal neovascularization
por: Miloudi, Sofiane, et al.
Publicado: (2022)

Cre-recombinase systems for induction of neuron-specific knockout models: a guide for biomedical researchers
por: Shcholok, Tetiana, et al.
Publicado: (2022)

Vil-Cre specific Schlafen 3 knockout mice exhibit sex-specific differences in intestinal differentiation markers and Schlafen family members expression levels
por: Vomhof-DeKrey, Emilie E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_k6eaahim2kl8q1qq5166juqbs8