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Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations
The aim of this study was to shed light on the neural substrate of conceptual representations starting from the construct of higher-order convergence zones and trying to evaluate the unitary or non-unitary nature of this construct. We used the ‘Thematic and Taxonomic Semantic (TTS) task’ to investig...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376965/ https://www.ncbi.nlm.nih.gov/pubmed/37508969 http://dx.doi.org/10.3390/brainsci13071037 |
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author | Bonnì, Sonia Borghi, Ilaria Maiella, Michele Casula, Elias Paolo Koch, Giacomo Caltagirone, Carlo Gainotti, Guido |
author_facet | Bonnì, Sonia Borghi, Ilaria Maiella, Michele Casula, Elias Paolo Koch, Giacomo Caltagirone, Carlo Gainotti, Guido |
author_sort | Bonnì, Sonia |
collection | PubMed |
description | The aim of this study was to shed light on the neural substrate of conceptual representations starting from the construct of higher-order convergence zones and trying to evaluate the unitary or non-unitary nature of this construct. We used the ‘Thematic and Taxonomic Semantic (TTS) task’ to investigate (a) the neural substrate of stimuli belonging to biological and artifact categories, (b) the format of stimuli presentation, i.e., verbal or pictorial, and (c) the relation between stimuli, i.e., categorial or contextual. We administered anodal transcranial direct current stimulation (tDCS) to different brain structures during the execution of the TTS task. Twenty healthy participants were enrolled and divided into two groups, one investigating the role of the anterior temporal lobes (ATL) and the other the temporo-parietal junctions (TPJ). Each participant underwent three sessions of stimulation to facilitate a control condition and to investigate the role of both hemispheres. Results showed that ATL stimulation influenced all conceptual representations in relation to the format of presentation (i.e., left-verbal and right-pictorial). Moreover, ATL stimulation modulated living categories and taxonomic relations specifically, whereas TPJ stimulation did not influence semantic task performances. |
format | Online Article Text |
id | pubmed-10376965 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103769652023-07-29 Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations Bonnì, Sonia Borghi, Ilaria Maiella, Michele Casula, Elias Paolo Koch, Giacomo Caltagirone, Carlo Gainotti, Guido Brain Sci Article The aim of this study was to shed light on the neural substrate of conceptual representations starting from the construct of higher-order convergence zones and trying to evaluate the unitary or non-unitary nature of this construct. We used the ‘Thematic and Taxonomic Semantic (TTS) task’ to investigate (a) the neural substrate of stimuli belonging to biological and artifact categories, (b) the format of stimuli presentation, i.e., verbal or pictorial, and (c) the relation between stimuli, i.e., categorial or contextual. We administered anodal transcranial direct current stimulation (tDCS) to different brain structures during the execution of the TTS task. Twenty healthy participants were enrolled and divided into two groups, one investigating the role of the anterior temporal lobes (ATL) and the other the temporo-parietal junctions (TPJ). Each participant underwent three sessions of stimulation to facilitate a control condition and to investigate the role of both hemispheres. Results showed that ATL stimulation influenced all conceptual representations in relation to the format of presentation (i.e., left-verbal and right-pictorial). Moreover, ATL stimulation modulated living categories and taxonomic relations specifically, whereas TPJ stimulation did not influence semantic task performances. MDPI 2023-07-07 /pmc/articles/PMC10376965/ /pubmed/37508969 http://dx.doi.org/10.3390/brainsci13071037 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bonnì, Sonia Borghi, Ilaria Maiella, Michele Casula, Elias Paolo Koch, Giacomo Caltagirone, Carlo Gainotti, Guido Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations |
title | Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations |
title_full | Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations |
title_fullStr | Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations |
title_full_unstemmed | Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations |
title_short | Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations |
title_sort | transcranial direct current stimulation effects on the neural substrate of conceptual representations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376965/ https://www.ncbi.nlm.nih.gov/pubmed/37508969 http://dx.doi.org/10.3390/brainsci13071037 |
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