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Comparison of Single-Stranded DNA Probes Conjugated with Magnetic Particles for Trans-Cleavage in Cas12a-Based Biosensors

Biosensors based on endonuclease Cas12 provide high specificity in pathogen detection. Sensitive detection using Cas12-based assays can be achieved using trans-cleaved DNA probes attached to simply separated carriers, such as magnetic particles (MPs). The aim of this work was to compare polyA, polyC...

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Detalles Bibliográficos
Autores principales: Ivanov, Aleksandr V., Safenkova, Irina V., Zherdev, Anatoly V., Wan, Yi, Dzantiev, Boris B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376970/
https://www.ncbi.nlm.nih.gov/pubmed/37504099
http://dx.doi.org/10.3390/bios13070700

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