Microphysiological Conditions Do Not Affect MDR1-Mediated Transport of Rhodamine 123 above an Artificial Proximal Tubule

Despite disadvantages, such as high cost and their poor predictive value, animal experiments are still the state of the art for pharmaceutical substance testing. One reason for this problem is the inability of standard cell culture methods to emulate the physiological environment necessary to recapi...

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Detalles Bibliográficos
Autores principales: Namazian Jam, Negin, Gottlöber, Felix, Hempel, Melanie, Dzekhtsiarova, Yuliya, Behrens, Stephan, Sonntag, Frank, Sradnick, Jan, Hugo, Christian, Schmieder, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10376999/
https://www.ncbi.nlm.nih.gov/pubmed/37509683
http://dx.doi.org/10.3390/biomedicines11072045

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