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The Role of NMDA Receptor Partial Antagonist, Carbamathione, as a Therapeutic Agent for Transient Global Ischemia

Carbamathione (Carb), an NMDA glutamate receptor partial antagonist, has potent neuroprotective functions against hypoxia- or ischemia-induced neuronal injury in cell- or animal-based stroke models. We used PC-12 cell cultures as a cell-based model and bilateral carotid artery occlusion (BCAO) for s...

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Detalles Bibliográficos
Autores principales: Modi, Jigar Pravinchandra, Shen, Wen, Menzie-Suderam, Janet, Xu, Hongyuan, Lin, Chun-Hua, Tao, Rui, Prentice, Howard M., Schloss, John, Wu, Jang-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377037/
https://www.ncbi.nlm.nih.gov/pubmed/37509524
http://dx.doi.org/10.3390/biomedicines11071885