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Antibody Dynamics Simulation—A Mathematical Exploration of Clonal Deletion and Somatic Hypermutation
We have employed mathematical modeling techniques to construct a comprehensive framework for elucidating the intricate response mechanisms of the immune system, facilitating a deeper understanding of B-cell clonal deletion and somatic hypermutation. Our improved model introduces innovative mechanism...
Autores principales: | Xu, Zhaobin, Peng, Qingzhi, Liu, Weidong, Demongeot, Jacques, Wei, Dongqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377040/ https://www.ncbi.nlm.nih.gov/pubmed/37509687 http://dx.doi.org/10.3390/biomedicines11072048 |
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