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Antibody Dynamics Simulation—A Mathematical Exploration of Clonal Deletion and Somatic Hypermutation

We have employed mathematical modeling techniques to construct a comprehensive framework for elucidating the intricate response mechanisms of the immune system, facilitating a deeper understanding of B-cell clonal deletion and somatic hypermutation. Our improved model introduces innovative mechanism...

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Detalles Bibliográficos
Autores principales: Xu, Zhaobin, Peng, Qingzhi, Liu, Weidong, Demongeot, Jacques, Wei, Dongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377040/
https://www.ncbi.nlm.nih.gov/pubmed/37509687
http://dx.doi.org/10.3390/biomedicines11072048

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