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Immunohistological Analysis of Lichen Sclerosus of the Foreskin in Pediatric Age: Could It Be Considered a Premalignant Lesion?
Background: A major worry of juvenile penile LS is potential malignant degeneration to spinocellular carcinoma (SCC) in adulthood. LS is characterized by increased CD8+ and CD57+ cells, dermal sclerosis, epidermal atrophy, and hyperkeratosis. p53 and Ki67 are reliable premalignant markers. Our aim w...
Autores principales: | Arena, Salvatore, Ieni, Antonio, Currò, Monica, Vaccaro, Mario, Di Fabrizio, Donatella, Cassaro, Fabiola, Bonfiglio, Roberta, Montalto, Angela Simona, Tuccari, Giovanni, Alibrandi, Angela, Impellizzeri, Pietro, Romeo, Carmelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377095/ https://www.ncbi.nlm.nih.gov/pubmed/37509626 http://dx.doi.org/10.3390/biomedicines11071986 |
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