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Immunohistological Analysis of Lichen Sclerosus of the Foreskin in Pediatric Age: Could It Be Considered a Premalignant Lesion?

Background: A major worry of juvenile penile LS is potential malignant degeneration to spinocellular carcinoma (SCC) in adulthood. LS is characterized by increased CD8+ and CD57+ cells, dermal sclerosis, epidermal atrophy, and hyperkeratosis. p53 and Ki67 are reliable premalignant markers. Our aim w...

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Detalles Bibliográficos
Autores principales: Arena, Salvatore, Ieni, Antonio, Currò, Monica, Vaccaro, Mario, Di Fabrizio, Donatella, Cassaro, Fabiola, Bonfiglio, Roberta, Montalto, Angela Simona, Tuccari, Giovanni, Alibrandi, Angela, Impellizzeri, Pietro, Romeo, Carmelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377095/
https://www.ncbi.nlm.nih.gov/pubmed/37509626
http://dx.doi.org/10.3390/biomedicines11071986

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