The Crystal Structure of the Hsp90-LA1011 Complex and the Mechanism by Which LA1011 May Improve the Prognosis of Alzheimer’s Disease

Functional changes in chaperone systems play a major role in the decline of cognition and contribute to neurological pathologies, such as Alzheimer’s disease (AD). While such a decline may occur naturally with age or with stress or trauma, the mechanisms involved have remained elusive. The current m...

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Detalles Bibliográficos
Autores principales: Roe, S. Mark, Török, Zsolt, McGown, Andrew, Horváth, Ibolya, Spencer, John, Pázmány, Tamás, Vigh, László, Prodromou, Chrisostomos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377191/
https://www.ncbi.nlm.nih.gov/pubmed/37509087
http://dx.doi.org/10.3390/biom13071051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377191/
https://www.ncbi.nlm.nih.gov/pubmed/37509087
http://dx.doi.org/10.3390/biom13071051

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