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A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia (MAINSTREAM): A Study Protocol
Primary Progressive Aphasia (PPA) is a syndrome due to different neurodegenerative disorders selectively disrupting language functions. PPA specialist care is underdeveloped. There are very few specialists (neurologists, psychiatrists, neuropsychologists, and speech therapists) and few hospital- or...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377301/ https://www.ncbi.nlm.nih.gov/pubmed/37508992 http://dx.doi.org/10.3390/brainsci13071060 |
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author | Cotelli, Maria Baglio, Francesca Manenti, Rosa Blasi, Valeria Galimberti, Daniela Gobbi, Elena Pagnoni, Ilaria Rossetto, Federica Rotondo, Emanuela Esposito, Valentina De Icco, Roberto Giudice, Carla Tassorelli, Cristina Catricalà, Eleonora Perini, Giulia Alaimo, Cristina Campana, Elena Benussi, Luisa Ghidoni, Roberta Binetti, Giuliano Carandini, Tiziana Cappa, Stefano Francesco |
author_facet | Cotelli, Maria Baglio, Francesca Manenti, Rosa Blasi, Valeria Galimberti, Daniela Gobbi, Elena Pagnoni, Ilaria Rossetto, Federica Rotondo, Emanuela Esposito, Valentina De Icco, Roberto Giudice, Carla Tassorelli, Cristina Catricalà, Eleonora Perini, Giulia Alaimo, Cristina Campana, Elena Benussi, Luisa Ghidoni, Roberta Binetti, Giuliano Carandini, Tiziana Cappa, Stefano Francesco |
author_sort | Cotelli, Maria |
collection | PubMed |
description | Primary Progressive Aphasia (PPA) is a syndrome due to different neurodegenerative disorders selectively disrupting language functions. PPA specialist care is underdeveloped. There are very few specialists (neurologists, psychiatrists, neuropsychologists, and speech therapists) and few hospital- or community-based services dedicated to the diagnosis and continuing care of people with PPA. Currently, healthcare systems struggle to provide adequate coverage of care that is too often fragmented, uncoordinated, and unresponsive to the needs of people with PPA and their families. Recently, attention has been gained by non-invasive brain stimulation techniques that allow a personalized treatment approach, such as transcranial Direct Current Stimulation (tDCS). The MAINSTREAM trial looks forward to introducing and evaluating therapeutic innovations such as tDCS coupled with language therapy in rehabilitation settings. A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM (ID: 3430931) was registered in the clinicaltrials.gov database (identifier: NCT05730023) on 15 February 2023. |
format | Online Article Text |
id | pubmed-10377301 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103773012023-07-29 A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia (MAINSTREAM): A Study Protocol Cotelli, Maria Baglio, Francesca Manenti, Rosa Blasi, Valeria Galimberti, Daniela Gobbi, Elena Pagnoni, Ilaria Rossetto, Federica Rotondo, Emanuela Esposito, Valentina De Icco, Roberto Giudice, Carla Tassorelli, Cristina Catricalà, Eleonora Perini, Giulia Alaimo, Cristina Campana, Elena Benussi, Luisa Ghidoni, Roberta Binetti, Giuliano Carandini, Tiziana Cappa, Stefano Francesco Brain Sci Article Primary Progressive Aphasia (PPA) is a syndrome due to different neurodegenerative disorders selectively disrupting language functions. PPA specialist care is underdeveloped. There are very few specialists (neurologists, psychiatrists, neuropsychologists, and speech therapists) and few hospital- or community-based services dedicated to the diagnosis and continuing care of people with PPA. Currently, healthcare systems struggle to provide adequate coverage of care that is too often fragmented, uncoordinated, and unresponsive to the needs of people with PPA and their families. Recently, attention has been gained by non-invasive brain stimulation techniques that allow a personalized treatment approach, such as transcranial Direct Current Stimulation (tDCS). The MAINSTREAM trial looks forward to introducing and evaluating therapeutic innovations such as tDCS coupled with language therapy in rehabilitation settings. A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM (ID: 3430931) was registered in the clinicaltrials.gov database (identifier: NCT05730023) on 15 February 2023. MDPI 2023-07-12 /pmc/articles/PMC10377301/ /pubmed/37508992 http://dx.doi.org/10.3390/brainsci13071060 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cotelli, Maria Baglio, Francesca Manenti, Rosa Blasi, Valeria Galimberti, Daniela Gobbi, Elena Pagnoni, Ilaria Rossetto, Federica Rotondo, Emanuela Esposito, Valentina De Icco, Roberto Giudice, Carla Tassorelli, Cristina Catricalà, Eleonora Perini, Giulia Alaimo, Cristina Campana, Elena Benussi, Luisa Ghidoni, Roberta Binetti, Giuliano Carandini, Tiziana Cappa, Stefano Francesco A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia (MAINSTREAM): A Study Protocol |
title | A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia (MAINSTREAM): A Study Protocol |
title_full | A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia (MAINSTREAM): A Study Protocol |
title_fullStr | A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia (MAINSTREAM): A Study Protocol |
title_full_unstemmed | A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia (MAINSTREAM): A Study Protocol |
title_short | A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia (MAINSTREAM): A Study Protocol |
title_sort | multimodal approach for clinical diagnosis and treatment of primary progressive aphasia (mainstream): a study protocol |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377301/ https://www.ncbi.nlm.nih.gov/pubmed/37508992 http://dx.doi.org/10.3390/brainsci13071060 |
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