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Quantitative Spatial Analysis of Neuroligin-3 mRNA Expression in the Enteric Nervous System Reveals a Potential Role in Neuronal–Glial Synapses and Reduced Expression in Nlgn3(R451C) Mice

Mutations in the Neuroligin-3 (Nlgn3) gene are implicated in autism spectrum disorder (ASD) and gastrointestinal (GI) dysfunction, but cellular Nlgn3 expression in the enteric nervous system remains to be characterised. We combined RNAScope in situ hybridization and immunofluorescence to measure Nlg...

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Detalles Bibliográficos
Autores principales: Herath, Madushani, Cho, Ellie, Marklund, Ulrika, Franks, Ashley E., Bornstein, Joel C., Hill-Yardin, Elisa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377306/
https://www.ncbi.nlm.nih.gov/pubmed/37509099
http://dx.doi.org/10.3390/biom13071063