Cargando…
MDM2 Inhibition in the Treatment of Glioblastoma: From Concept to Clinical Investigation
Inhibition of the interaction between MDM2 and p53 has emerged as a promising strategy for combating cancer, including the treatment of glioblastoma (GBM). Numerous MDM2 inhibitors have been developed and are currently undergoing rigorous testing for their potential in GBM therapy. Encouraging resul...
Autores principales: | Pellot Ortiz, Karolina I., Rechberger, Julian S., Nonnenbroich, Leo F., Daniels, David J., Sarkaria, Jann N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377337/ https://www.ncbi.nlm.nih.gov/pubmed/37509518 http://dx.doi.org/10.3390/biomedicines11071879 |
Ejemplares similares
-
DIPG-15. CONCURRENT GB-13 (IL13.E13K-PE4E) IMPROVES THE EFFICACY OF RADIATION THERAPY IN DIFFUSE INTRINSIC PONTINE GLIOMA
por: Rechberger, Julian S, et al.
Publicado: (2023) -
HGG-10. Efficacy of convection-enhanced delivery of GB-13 (IL13.E13K-PE4E) in an orthotopic xenograft model of high-grade glioma is predicated on IL-13Rα2 expression.
por: Rechberger, Julian, et al.
Publicado: (2022) -
LOCL-07 LOCO-REGIONAL INFUSION OF GB-13 (IL13.E13K-PE4E) AS A POTENTIALLY PROMISING TREATMENT FOR RECURRENT HIGH-GRADE GLIOMA
por: Rechberger, Julian, et al.
Publicado: (2022) -
Nanoparticle Strategies to Improve the Delivery of Anticancer Drugs across the Blood–Brain Barrier to Treat Brain Tumors
por: Vanbilloen, Wouter J. F., et al.
Publicado: (2023) -
Editorial: Targeted Therapies for Glioblastoma: A Critical Appraisal
por: Gupta, Shiv K., et al.
Publicado: (2019)