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Essential Oils: Chemistry and Pharmacological Activities

In this review, we provide an overview of the current understanding of the main mechanisms of pharmacological action of essential oils and their components in various biological systems. A brief introduction on essential oil chemistry is presented to better understand the relationship of chemical as...

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Autores principales: de Sousa, Damião P., Damasceno, Renan Oliveira S., Amorati, Riccardo, Elshabrawy, Hatem A., de Castro, Ricardo D., Bezerra, Daniel P., Nunes, Vitória Regina V., Gomes, Rebeca C., Lima, Tamires C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377445/
https://www.ncbi.nlm.nih.gov/pubmed/37509180
http://dx.doi.org/10.3390/biom13071144
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author de Sousa, Damião P.
Damasceno, Renan Oliveira S.
Amorati, Riccardo
Elshabrawy, Hatem A.
de Castro, Ricardo D.
Bezerra, Daniel P.
Nunes, Vitória Regina V.
Gomes, Rebeca C.
Lima, Tamires C.
author_facet de Sousa, Damião P.
Damasceno, Renan Oliveira S.
Amorati, Riccardo
Elshabrawy, Hatem A.
de Castro, Ricardo D.
Bezerra, Daniel P.
Nunes, Vitória Regina V.
Gomes, Rebeca C.
Lima, Tamires C.
author_sort de Sousa, Damião P.
collection PubMed
description In this review, we provide an overview of the current understanding of the main mechanisms of pharmacological action of essential oils and their components in various biological systems. A brief introduction on essential oil chemistry is presented to better understand the relationship of chemical aspects with the bioactivity of these products. Next, the antioxidant, anti-inflammatory, antitumor, and antimicrobial activities are discussed. The mechanisms of action against various types of viruses are also addressed. The data show that the multiplicity of pharmacological properties of essential oils occurs due to the chemical diversity in their composition and their ability to interfere with biological processes at cellular and multicellular levels via interaction with various biological targets. Therefore, these natural products can be a promising source for the development of new drugs.
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spelling pubmed-103774452023-07-29 Essential Oils: Chemistry and Pharmacological Activities de Sousa, Damião P. Damasceno, Renan Oliveira S. Amorati, Riccardo Elshabrawy, Hatem A. de Castro, Ricardo D. Bezerra, Daniel P. Nunes, Vitória Regina V. Gomes, Rebeca C. Lima, Tamires C. Biomolecules Review In this review, we provide an overview of the current understanding of the main mechanisms of pharmacological action of essential oils and their components in various biological systems. A brief introduction on essential oil chemistry is presented to better understand the relationship of chemical aspects with the bioactivity of these products. Next, the antioxidant, anti-inflammatory, antitumor, and antimicrobial activities are discussed. The mechanisms of action against various types of viruses are also addressed. The data show that the multiplicity of pharmacological properties of essential oils occurs due to the chemical diversity in their composition and their ability to interfere with biological processes at cellular and multicellular levels via interaction with various biological targets. Therefore, these natural products can be a promising source for the development of new drugs. MDPI 2023-07-18 /pmc/articles/PMC10377445/ /pubmed/37509180 http://dx.doi.org/10.3390/biom13071144 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
de Sousa, Damião P.
Damasceno, Renan Oliveira S.
Amorati, Riccardo
Elshabrawy, Hatem A.
de Castro, Ricardo D.
Bezerra, Daniel P.
Nunes, Vitória Regina V.
Gomes, Rebeca C.
Lima, Tamires C.
Essential Oils: Chemistry and Pharmacological Activities
title Essential Oils: Chemistry and Pharmacological Activities
title_full Essential Oils: Chemistry and Pharmacological Activities
title_fullStr Essential Oils: Chemistry and Pharmacological Activities
title_full_unstemmed Essential Oils: Chemistry and Pharmacological Activities
title_short Essential Oils: Chemistry and Pharmacological Activities
title_sort essential oils: chemistry and pharmacological activities
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377445/
https://www.ncbi.nlm.nih.gov/pubmed/37509180
http://dx.doi.org/10.3390/biom13071144
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