Goldilocks Dilemma: LPS Works Both as the Initial Target and a Barrier for the Antimicrobial Action of Cationic AMPs on E. coli

Antimicrobial peptides (AMPs) are generally membrane-active compounds that physically disrupt bacterial membranes. Despite extensive research, the precise mode of action of AMPs is still a topic of great debate. This work demonstrates that the initial interaction between the Gram-negative E. coli an...

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Detalles Bibliográficos
Autores principales: Jakubec, Martin, Rylandsholm, Fredrik G., Rainsford, Philip, Silk, Mitchell, Bril’kov, Maxim, Kristoffersen, Tone, Juskewitz, Eric, Ericson, Johanna U., Svendsen, John Sigurd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377513/
https://www.ncbi.nlm.nih.gov/pubmed/37509189
http://dx.doi.org/10.3390/biom13071155

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