Cargando…

Circulating Natural Killer Cells as Prognostic Value for Non-Small-Cell Lung Cancer Patients Treated with Immune Checkpoint Inhibitors: Correlation with Sarcopenia

SIMPLE SUMMARY: In this study, we provide a basal and longitudinal evaluation of immune cells in advanced non-small-cell lung cancer (NSCLC) patients undergoing PD-1 or PD-L1 blockade. We aimed to explore if any data could be predictive of better outcomes and long-term survival and to detect eventua...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tenuta, Marta, Pandozzi, Carla, Sciarra, Francesca, Campolo, Federica, Gelibter, Alain J., Sirgiovanni, Grazia, Cortesi, Enrico, Lenzi, Andrea, Isidori, Andrea M., Sbardella, Emilia, Venneri, Mary Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377538/ https://www.ncbi.nlm.nih.gov/pubmed/37509255 http://dx.doi.org/10.3390/cancers15143592

Ejemplares similares

Impact of Sarcopenia and Inflammation on Patients with Advanced Non-Small Cell Lung Cancer (NCSCL) Treated with Immune Checkpoint Inhibitors (ICIs): A Prospective Study
por: Tenuta, Marta, et al.
Publicado: (2021)

OR21-6 Diabetic Cardiac Hypertrophy Is Associated With Viscoelastic Changes In Myocardial Contraction: Role Of Hsa-mir-122-5p On Extracellular Matrix.
por: Isidori, Andrea, et al.
Publicado: (2019)

cAMP-specific phosphodiesterase 8A and 8B isoforms are differentially expressed in human testis and Leydig cell tumor
por: Campolo, Federica, et al.
Publicado: (2022)

SUN-238 Clinical Presentation, Management And Follow-up Of 83 Leydig Cell Tumors Of The Testis: A Prospective Case-cohort Study.
por: Isidori, Andrea, et al.
Publicado: (2019)

Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study
por: Pozza, Carlotta, et al.
Publicado: (2019)

Disruption of Circadian Rhythms: A Crucial Factor in the Etiology of Infertility
por: Sciarra, Francesca, et al.
Publicado: (2020)

The Diagnostic Potential of the Human Blood Microbiome: Are We Dreaming or Awake?
por: Sciarra, Francesca, et al.
Publicado: (2023)

Glycometabolic Alterations in Secondary Adrenal Insufficiency: Does Replacement Therapy Play a Role?
por: Graziadio, Chiara, et al.
Publicado: (2018)

Platelet-derived circRNAs signature in patients with gastroenteropancreatic neuroendocrine tumors
por: Campolo, Federica, et al.
Publicado: (2023)

Gender-Specific Impact of Sex Hormones on the Immune System
por: Sciarra, Francesca, et al.
Publicado: (2023)

Status of correlation between BMI and response to immunocheck-point inhibitor in advanced non-small-cell lung cancer
por: Gelibter, Alain, et al.
Publicado: (2020)

Clinical, Diagnostic, and Therapeutic Aspects of Growth Hormone Deficiency During the Transition Period: Review of the Literature
por: Spaziani, Matteo, et al.
Publicado: (2021)

Correction: Pituitary T1 signal intensity at magnetic resonance imaging is reduced in patients with obesity: results from the CHIASM study
por: Puliani, Giulia, et al.
Publicado: (2023)

Pituitary T1 signal intensity at magnetic resonance imaging is reduced in patients with obesity: results from the CHIASM study
por: Puliani, Giulia, et al.
Publicado: (2023)

Epicardial Adipose Tissue: A Novel Potential Imaging Marker of Comorbidities Caused by Chronic Inflammation
por: Tarsitano, Maria Grazia, et al.
Publicado: (2022)

Carcinoid Syndrome: Preclinical Models and Future Therapeutic Strategies
por: Vitale, Giovanni, et al.
Publicado: (2023)

Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study
por: Sciortino, Carolina, et al.
Publicado: (2022)

Evaluation of Efficacy of ALK Inhibitors According to Body Mass Index in ALK Rearranged NSCLC Patients—A Retrospective Observational Study
por: Siringo, Marco, et al.
Publicado: (2023)

Extrathyroidal Calcitonin Secreting Tumors: Pancreatic Neuroendocrine Tumors in Patients With Multinodular Goiter: Two Case Reports
por: Giannetta, Elisa, et al.
Publicado: (2016)

Non-Canonical Effects of ACTH: Insights Into Adrenal Insufficiency
por: Hasenmajer, Valeria, et al.
Publicado: (2021)

Once upon a Testis: The Tale of Cyclic Nucleotide Phosphodiesterase in Testicular Cancers
por: Campolo, Federica, et al.
Publicado: (2023)

The NO/cGMP/PKG pathway in platelets: The therapeutic potential of PDE5 inhibitors in platelet disorders
por: Degjoni, Anisa, et al.
Publicado: (2022)

LBMON274 Total Osteocalcin Levels Are Independently Associated With Worse Testicular Function And A Higher Degree Of HPG Axis Activation In Klinefelter Syndrome
por: Carlomagno, Francesco, et al.
Publicado: (2022)

A Novel MAX Gene Mutation Variant in a Patient With Multiple and “Composite” Neuroendocrine–Neuroblastic Tumors
por: Pozza, Carlotta, et al.
Publicado: (2020)

The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy
por: Quatrini, Linda, et al.
Publicado: (2020)

Burned-Out Testicular Cancer: Really a Different History?
por: Mosillo, Claudia, et al.
Publicado: (2017)

Rheumatic Diseases Development in Patients Treated by Anti-PD1 Immune Checkpoint Inhibitors: A Single-Centre Descriptive Study
por: Ceccarelli, Fulvia, et al.
Publicado: (2023)

Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells
por: Kim, Nayoung, et al.
Publicado: (2018)

Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28
por: Mariotti, F.R., et al.
Publicado: (2020)

Sphingomyelin is a prospective metabolic immune checkpoint for natural killer cells
por: Ma, Hongdi, et al.
Publicado: (2023)

Comparison of Two Blood-Based Genotyping Tests to Investigate the KRAS G12C Mutation in Patients with Non-Small-Cell Lung Cancer at Failure of First-Line Treatments
por: Nicolazzo, Chiara, et al.
Publicado: (2021)

Renal Function Outcomes in Metastatic Non-Small-Cell Lung Carcinoma Patients Treated with Chemotherapy or Immune Checkpoint Inhibitors: An Unexpected Scenario
por: Trevisani, Francesco, et al.
Publicado: (2022)

Human genital tracts microbiota: dysbiosis crucial for infertility
por: Venneri, M. A., et al.
Publicado: (2022)

Molecular checkpoints controlling natural killer cell activation and their modulation for cancer immunotherapy
por: Kwon, Hyung-Joon, et al.
Publicado: (2017)

Identification of druggable inhibitory immune checkpoints on Natural Killer cells in COVID-19
por: Demaria, Olivier, et al.
Publicado: (2020)

Immune checkpoint molecules in natural killer cells as potential targets for cancer immunotherapy
por: Cao, Yuqing, et al.
Publicado: (2020)

TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity
por: Bi, Jiacheng, et al.
Publicado: (2021)

Inhibitory Receptors and Immune Checkpoints Regulating Natural Killer Cell Responses to Cancer
por: Buckle, Irina, et al.
Publicado: (2021)

Long‐term remission of small cell lung cancer after reactivation of tuberculosis following immune‐checkpoint blockade: A case report
por: Sirgiovanni, Mattia, et al.
Publicado: (2021)

Transient Disappearance of RAS Mutant Clones in Plasma: A Counterintuitive Clinical Use of EGFR Inhibitors in RAS Mutant Metastatic Colorectal Cancer
por: Raimondi, Cristina, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vpq4kbete3j2d2eq1kref6v2l9