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Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells

In the last few decades, evidence has surfaced that weak radiofrequency (RF) fields can influence biological systems. This work aims to improve our understanding of how externally applied weak RF fields alter concentrations of chemical parameters that characterize oxidative stress. We conducted a se...

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Detalles Bibliográficos
Autores principales: Gurhan, Hakki, Bajtoš, Marek, Barnes, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377549/
https://www.ncbi.nlm.nih.gov/pubmed/37509147
http://dx.doi.org/10.3390/biom13071112
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author Gurhan, Hakki
Bajtoš, Marek
Barnes, Frank
author_facet Gurhan, Hakki
Bajtoš, Marek
Barnes, Frank
author_sort Gurhan, Hakki
collection PubMed
description In the last few decades, evidence has surfaced that weak radiofrequency (RF) fields can influence biological systems. This work aims to improve our understanding of how externally applied weak RF fields alter concentrations of chemical parameters that characterize oxidative stress. We conducted a series of experiments to investigate the effects of applying weak RF magnetic fields within the 3–5 MHz region on mitochondrial respiration in both human fibrosarcoma and fibroblast cells over a period of four days. Our experimental data show that RF fields between 3 and 5 MHz were able to change the modulation of mitochondrial signaling by changing the cell growth, mitochondrial mass, and oxidative stress. Exposure to RF fields at 4.2 MHz significantly increased the mitochondrial mass and oxidative stress in fibrosarcoma cells. There are substantial concerns that extended exposure to weak RF fields can lead to health effects. The ability to control these parameters by external magnetic fields may have important clinical implications.
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spelling pubmed-103775492023-07-29 Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells Gurhan, Hakki Bajtoš, Marek Barnes, Frank Biomolecules Article In the last few decades, evidence has surfaced that weak radiofrequency (RF) fields can influence biological systems. This work aims to improve our understanding of how externally applied weak RF fields alter concentrations of chemical parameters that characterize oxidative stress. We conducted a series of experiments to investigate the effects of applying weak RF magnetic fields within the 3–5 MHz region on mitochondrial respiration in both human fibrosarcoma and fibroblast cells over a period of four days. Our experimental data show that RF fields between 3 and 5 MHz were able to change the modulation of mitochondrial signaling by changing the cell growth, mitochondrial mass, and oxidative stress. Exposure to RF fields at 4.2 MHz significantly increased the mitochondrial mass and oxidative stress in fibrosarcoma cells. There are substantial concerns that extended exposure to weak RF fields can lead to health effects. The ability to control these parameters by external magnetic fields may have important clinical implications. MDPI 2023-07-13 /pmc/articles/PMC10377549/ /pubmed/37509147 http://dx.doi.org/10.3390/biom13071112 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gurhan, Hakki
Bajtoš, Marek
Barnes, Frank
Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells
title Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells
title_full Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells
title_fullStr Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells
title_full_unstemmed Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells
title_short Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells
title_sort weak radiofrequency field effects on chemical parameters that characterize oxidative stress in human fibrosarcoma and fibroblast cells
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377549/
https://www.ncbi.nlm.nih.gov/pubmed/37509147
http://dx.doi.org/10.3390/biom13071112
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