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Methadone Potentiates the Cytotoxicity of Temozolomide by Impairing Calcium Homeostasis and Dysregulation of PARP in Glioblastoma Cells
SIMPLE SUMMARY: Temozolomide is a widely used chemotherapeutic agent for the treatment of glioblastoma multiforme, but its efficacy is often severely limited by cell resistance to this treatment. Opioids have been found to increase the sensitivity of glioblastoma cells to temozolomide. However, the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377588/ https://www.ncbi.nlm.nih.gov/pubmed/37509230 http://dx.doi.org/10.3390/cancers15143567 |