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From Self-Assembly of Colloidal Crystals toward Ordered Porous Layer Interferometry
Interferometry-based, reflectometric, label-free biosensors have made significant progress in the analysis of molecular interactions after years of development. The design of interference substrates is a key research topic for these biosensors, and many studies have focused on porous films prepared...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377590/ https://www.ncbi.nlm.nih.gov/pubmed/37504128 http://dx.doi.org/10.3390/bios13070730 |
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author | Wan, Yi-Zhen Qian, Weiping |
author_facet | Wan, Yi-Zhen Qian, Weiping |
author_sort | Wan, Yi-Zhen |
collection | PubMed |
description | Interferometry-based, reflectometric, label-free biosensors have made significant progress in the analysis of molecular interactions after years of development. The design of interference substrates is a key research topic for these biosensors, and many studies have focused on porous films prepared by top-down methods such as porous silicon and anodic aluminum oxide. Lately, more research has been conducted on ordered porous layer interferometry (OPLI), which uses ordered porous colloidal crystal films as interference substrates. These films are made using self-assembly techniques, which is the bottom-up approach. They also offer several advantages for biosensing applications, such as budget cost, adjustable porosity, and high structural consistency. This review will briefly explain the fundamental components of self-assembled materials and thoroughly discuss various self-assembly techniques in depth. We will also summarize the latest studies that used the OPLI technique for label-free biosensing applications and divide them into several aspects for further discussion. Then, we will comprehensively evaluate the strengths and weaknesses of self-assembly techniques and discuss possible future research directions. Finally, we will outlook the upcoming challenges and opportunities for label-free biosensing using the OPLI technique. |
format | Online Article Text |
id | pubmed-10377590 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103775902023-07-29 From Self-Assembly of Colloidal Crystals toward Ordered Porous Layer Interferometry Wan, Yi-Zhen Qian, Weiping Biosensors (Basel) Review Interferometry-based, reflectometric, label-free biosensors have made significant progress in the analysis of molecular interactions after years of development. The design of interference substrates is a key research topic for these biosensors, and many studies have focused on porous films prepared by top-down methods such as porous silicon and anodic aluminum oxide. Lately, more research has been conducted on ordered porous layer interferometry (OPLI), which uses ordered porous colloidal crystal films as interference substrates. These films are made using self-assembly techniques, which is the bottom-up approach. They also offer several advantages for biosensing applications, such as budget cost, adjustable porosity, and high structural consistency. This review will briefly explain the fundamental components of self-assembled materials and thoroughly discuss various self-assembly techniques in depth. We will also summarize the latest studies that used the OPLI technique for label-free biosensing applications and divide them into several aspects for further discussion. Then, we will comprehensively evaluate the strengths and weaknesses of self-assembly techniques and discuss possible future research directions. Finally, we will outlook the upcoming challenges and opportunities for label-free biosensing using the OPLI technique. MDPI 2023-07-13 /pmc/articles/PMC10377590/ /pubmed/37504128 http://dx.doi.org/10.3390/bios13070730 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Wan, Yi-Zhen Qian, Weiping From Self-Assembly of Colloidal Crystals toward Ordered Porous Layer Interferometry |
title | From Self-Assembly of Colloidal Crystals toward Ordered Porous Layer Interferometry |
title_full | From Self-Assembly of Colloidal Crystals toward Ordered Porous Layer Interferometry |
title_fullStr | From Self-Assembly of Colloidal Crystals toward Ordered Porous Layer Interferometry |
title_full_unstemmed | From Self-Assembly of Colloidal Crystals toward Ordered Porous Layer Interferometry |
title_short | From Self-Assembly of Colloidal Crystals toward Ordered Porous Layer Interferometry |
title_sort | from self-assembly of colloidal crystals toward ordered porous layer interferometry |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377590/ https://www.ncbi.nlm.nih.gov/pubmed/37504128 http://dx.doi.org/10.3390/bios13070730 |
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