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Side Chain-Modified Benzothiazinone Derivatives with Anti-Mycobacterial Activity

Tuberculosis (TB) is a leading infectious disease with serious antibiotic resistance. The benzothiazinone (BTZ) scaffold PBTZ169 kills Mycobacterium tuberculosis (Mtb) through the inhibition of the essential cell wall enzyme decaprenylphosphoryl-β-D-ribose 2’-oxidase (DprE1). PBTZ169 shows anti-TB p...

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Detalles Bibliográficos
Autores principales:	Fan, Dongguang, Wang, Bin, Stelitano, Giovanni, Savková, Karin, Riabova, Olga, Shi, Rui, Wu, Xiaomei, Chiarelli, Laurent R., Mikušová, Katarína, Makarov, Vadim, Lu, Yu, Hong, Yuzhi, Qiao, Chunhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377601/ https://www.ncbi.nlm.nih.gov/pubmed/37509615 http://dx.doi.org/10.3390/biomedicines11071975

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