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iPSC-Derived Glioblastoma Cells Have Enhanced Stemness Wnt/β-Catenin Activity Which Is Negatively Regulated by Wnt Antagonist sFRP4

SIMPLE SUMMARY: Cancer is the second most complex disease after cardiovascular disease. Glioblastoma multiforme (GBM) is a heterogeneous tumor in which the small population of cancer stem cells (CSCs) confers tumors with stemness, relapse and chemotherapeutic resistance. The complete knowledge of th...

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Detalles Bibliográficos
Autores principales: Yasmin, Ishmat Ara, Dharmarajan, Arun, Warrier, Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377620/
https://www.ncbi.nlm.nih.gov/pubmed/37509281
http://dx.doi.org/10.3390/cancers15143622