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Extracellular Matrix Proteomics: The mdx-4cv Mouse Diaphragm as a Surrogate for Studying Myofibrosis in Dystrophinopathy

The progressive degeneration of the skeletal musculature in Duchenne muscular dystrophy is accompanied by reactive myofibrosis, fat substitution, and chronic inflammation. Fibrotic changes and reduced tissue elasticity correlate with the loss in motor function in this X-chromosomal disorder. Thus, a...

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Detalles Bibliográficos
Autores principales:	Dowling, Paul, Gargan, Stephen, Zweyer, Margit, Swandulla, Dieter, Ohlendieck, Kay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377647/ https://www.ncbi.nlm.nih.gov/pubmed/37509144 http://dx.doi.org/10.3390/biom13071108

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