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Diagnosis of Obstructive Sleep Apnea Using Feature Selection, Classification Methods, and Data Grouping Based Age, Sex, and Race

Obstructive sleep apnea (OSA) is a prevalent sleep disorder that affects approximately 3–7% of males and 2–5% of females. In the United States alone, 50–70 million adults suffer from various sleep disorders. OSA is characterized by recurrent episodes of breathing cessation during sleep, thereby lead...

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Autores principales: Sheta, Alaa, Thaher, Thaer, Surani, Salim R., Turabieh, Hamza, Braik, Malik, Too, Jingwei, Abu-El-Rub, Noor, Mafarjah, Majdi, Chantar, Hamouda, Subramanian, Shyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377846/
https://www.ncbi.nlm.nih.gov/pubmed/37510161
http://dx.doi.org/10.3390/diagnostics13142417
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author Sheta, Alaa
Thaher, Thaer
Surani, Salim R.
Turabieh, Hamza
Braik, Malik
Too, Jingwei
Abu-El-Rub, Noor
Mafarjah, Majdi
Chantar, Hamouda
Subramanian, Shyam
author_facet Sheta, Alaa
Thaher, Thaer
Surani, Salim R.
Turabieh, Hamza
Braik, Malik
Too, Jingwei
Abu-El-Rub, Noor
Mafarjah, Majdi
Chantar, Hamouda
Subramanian, Shyam
author_sort Sheta, Alaa
collection PubMed
description Obstructive sleep apnea (OSA) is a prevalent sleep disorder that affects approximately 3–7% of males and 2–5% of females. In the United States alone, 50–70 million adults suffer from various sleep disorders. OSA is characterized by recurrent episodes of breathing cessation during sleep, thereby leading to adverse effects such as daytime sleepiness, cognitive impairment, and reduced concentration. It also contributes to an increased risk of cardiovascular conditions and adversely impacts patient overall quality of life. As a result, numerous researchers have focused on developing automated detection models to identify OSA and address these limitations effectively and accurately. This study explored the potential benefits of utilizing machine learning methods based on demographic information for diagnosing the OSA syndrome. We gathered a comprehensive dataset from the Torr Sleep Center in Corpus Christi, Texas, USA. The dataset comprises 31 features, including demographic characteristics such as race, age, sex, BMI, Epworth score, M. Friedman tongue position, snoring, and more. We devised a novel process encompassing pre-processing, data grouping, feature selection, and machine learning classification methods to achieve the research objectives. The classification methods employed in this study encompass decision tree (DT), naive Bayes (NB), k-nearest neighbor (kNN), support vector machine (SVM), linear discriminant analysis (LDA), logistic regression (LR), and subspace discriminant (Ensemble) classifiers. Through rigorous experimentation, the results indicated the superior performance of the optimized kNN and SVM classifiers for accurately classifying sleep apnea. Moreover, significant enhancements in model accuracy were observed when utilizing the selected demographic variables and employing data grouping techniques. For instance, the accuracy percentage demonstrated an approximate improvement of 4.5%, 5%, and 10% with the feature selection approach when applied to the grouped data of Caucasians, females, and individuals aged 50 or below, respectively. Furthermore, a comparison with prior studies confirmed that effective data grouping and proper feature selection yielded superior performance in OSA detection when combined with an appropriate classification method. Overall, the findings of this research highlight the importance of leveraging demographic information, employing proper feature selection techniques, and utilizing optimized classification models for accurate and efficient OSA diagnosis.
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spelling pubmed-103778462023-07-29 Diagnosis of Obstructive Sleep Apnea Using Feature Selection, Classification Methods, and Data Grouping Based Age, Sex, and Race Sheta, Alaa Thaher, Thaer Surani, Salim R. Turabieh, Hamza Braik, Malik Too, Jingwei Abu-El-Rub, Noor Mafarjah, Majdi Chantar, Hamouda Subramanian, Shyam Diagnostics (Basel) Article Obstructive sleep apnea (OSA) is a prevalent sleep disorder that affects approximately 3–7% of males and 2–5% of females. In the United States alone, 50–70 million adults suffer from various sleep disorders. OSA is characterized by recurrent episodes of breathing cessation during sleep, thereby leading to adverse effects such as daytime sleepiness, cognitive impairment, and reduced concentration. It also contributes to an increased risk of cardiovascular conditions and adversely impacts patient overall quality of life. As a result, numerous researchers have focused on developing automated detection models to identify OSA and address these limitations effectively and accurately. This study explored the potential benefits of utilizing machine learning methods based on demographic information for diagnosing the OSA syndrome. We gathered a comprehensive dataset from the Torr Sleep Center in Corpus Christi, Texas, USA. The dataset comprises 31 features, including demographic characteristics such as race, age, sex, BMI, Epworth score, M. Friedman tongue position, snoring, and more. We devised a novel process encompassing pre-processing, data grouping, feature selection, and machine learning classification methods to achieve the research objectives. The classification methods employed in this study encompass decision tree (DT), naive Bayes (NB), k-nearest neighbor (kNN), support vector machine (SVM), linear discriminant analysis (LDA), logistic regression (LR), and subspace discriminant (Ensemble) classifiers. Through rigorous experimentation, the results indicated the superior performance of the optimized kNN and SVM classifiers for accurately classifying sleep apnea. Moreover, significant enhancements in model accuracy were observed when utilizing the selected demographic variables and employing data grouping techniques. For instance, the accuracy percentage demonstrated an approximate improvement of 4.5%, 5%, and 10% with the feature selection approach when applied to the grouped data of Caucasians, females, and individuals aged 50 or below, respectively. Furthermore, a comparison with prior studies confirmed that effective data grouping and proper feature selection yielded superior performance in OSA detection when combined with an appropriate classification method. Overall, the findings of this research highlight the importance of leveraging demographic information, employing proper feature selection techniques, and utilizing optimized classification models for accurate and efficient OSA diagnosis. MDPI 2023-07-20 /pmc/articles/PMC10377846/ /pubmed/37510161 http://dx.doi.org/10.3390/diagnostics13142417 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sheta, Alaa
Thaher, Thaer
Surani, Salim R.
Turabieh, Hamza
Braik, Malik
Too, Jingwei
Abu-El-Rub, Noor
Mafarjah, Majdi
Chantar, Hamouda
Subramanian, Shyam
Diagnosis of Obstructive Sleep Apnea Using Feature Selection, Classification Methods, and Data Grouping Based Age, Sex, and Race
title Diagnosis of Obstructive Sleep Apnea Using Feature Selection, Classification Methods, and Data Grouping Based Age, Sex, and Race
title_full Diagnosis of Obstructive Sleep Apnea Using Feature Selection, Classification Methods, and Data Grouping Based Age, Sex, and Race
title_fullStr Diagnosis of Obstructive Sleep Apnea Using Feature Selection, Classification Methods, and Data Grouping Based Age, Sex, and Race
title_full_unstemmed Diagnosis of Obstructive Sleep Apnea Using Feature Selection, Classification Methods, and Data Grouping Based Age, Sex, and Race
title_short Diagnosis of Obstructive Sleep Apnea Using Feature Selection, Classification Methods, and Data Grouping Based Age, Sex, and Race
title_sort diagnosis of obstructive sleep apnea using feature selection, classification methods, and data grouping based age, sex, and race
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377846/
https://www.ncbi.nlm.nih.gov/pubmed/37510161
http://dx.doi.org/10.3390/diagnostics13142417
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