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CXCR2 Is Deregulated in ALS Spinal Cord and Its Activation Triggers Apoptosis in Motor Neuron-Like Cells Overexpressing hSOD1-G93A
Amyotrophic lateral sclerosis (ALS) is a multifactorial neurodegenerative disease characterized by progressive depletion of motor neurons (MNs). Recent evidence suggests a role in ALS pathology for the C-X-C motif chemokine receptor 2 (CXCR2), whose expression was found increased at both mRNA and pr...
Autores principales: | La Cognata, Valentina, D’Amico, Agata Grazia, Maugeri, Grazia, Morello, Giovanna, Guarnaccia, Maria, Magrì, Benedetta, Aronica, Eleonora, D’Agata, Velia, Cavallaro, Sebastiano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377984/ https://www.ncbi.nlm.nih.gov/pubmed/37508478 http://dx.doi.org/10.3390/cells12141813 |
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