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Mechanisms of PARP-Inhibitor-Resistance in BRCA-Mutated Breast Cancer and New Therapeutic Approaches
SIMPLE SUMMARY: Poly (ADP-ribose) polymerase (PARP) inhibitors treat breast and ovarian cancers. PARP-inhibition (PARPi), which affects cell survival by re-regulating DNA repair mechanisms, is known as one of the promising methods in terms of treatment protocols. However, resistance to PARP inhibito...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378018/ https://www.ncbi.nlm.nih.gov/pubmed/37509303 http://dx.doi.org/10.3390/cancers15143642 |