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Autophagy Inhibition with Chloroquine Increased Pro-Apoptotic Potential of New Aziridine-Hydrazide Hydrazone Derivatives against Glioblastoma Cells

Tumor therapy escape due to undesired side effects induced by treatment, such as prosurvival autophagy or cellular senescence, is one of the key mechanisms of resistance that eventually leads to tumor dormancy and recurrence. Glioblastoma is the most frequent and practically incurable neoplasm of th...

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Detalles Bibliográficos
Autores principales: Witusik-Perkowska, Monika, Głowacka, Pola, Pieczonka, Adam M., Świderska, Ewa, Pudlarz, Agnieszka, Rachwalski, Michał, Szymańska, Julia, Zakrzewska, Magdalena, Jaskólski, Dariusz J., Szemraj, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378024/
https://www.ncbi.nlm.nih.gov/pubmed/37508570
http://dx.doi.org/10.3390/cells12141906