Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis

The induced membrane technique is an innovative approach for repairing critical bone defects and has been applied recently in patients with congenital pseudarthrosis of the tibia (CPT). CPT is frequently associated with neurofibromatosis type 1 (NF1). Here, we briefly describe the clinical results o...

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Autores principales: Klein, Céline, Gindraux, Florelle, Masquelet, Alain-Charles, Mentaverri, Romuald, Gouron, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378057/
https://www.ncbi.nlm.nih.gov/pubmed/37508581
http://dx.doi.org/10.3390/cells12141918
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author Klein, Céline
Gindraux, Florelle
Masquelet, Alain-Charles
Mentaverri, Romuald
Gouron, Richard
author_facet Klein, Céline
Gindraux, Florelle
Masquelet, Alain-Charles
Mentaverri, Romuald
Gouron, Richard
author_sort Klein, Céline
collection PubMed
description The induced membrane technique is an innovative approach for repairing critical bone defects and has been applied recently in patients with congenital pseudarthrosis of the tibia (CPT). CPT is frequently associated with neurofibromatosis type 1 (NF1). Here, we briefly describe the clinical results of the induced membrane technique in NF1-deficient patients with CPT and in an animal model of CPT. Furthermore, we discuss the hypotheses used to explain inconsistent outcomes for the induced membrane technique in CPT–especially when associated with NF1.
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spelling pubmed-103780572023-07-29 Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis Klein, Céline Gindraux, Florelle Masquelet, Alain-Charles Mentaverri, Romuald Gouron, Richard Cells Editorial The induced membrane technique is an innovative approach for repairing critical bone defects and has been applied recently in patients with congenital pseudarthrosis of the tibia (CPT). CPT is frequently associated with neurofibromatosis type 1 (NF1). Here, we briefly describe the clinical results of the induced membrane technique in NF1-deficient patients with CPT and in an animal model of CPT. Furthermore, we discuss the hypotheses used to explain inconsistent outcomes for the induced membrane technique in CPT–especially when associated with NF1. MDPI 2023-07-24 /pmc/articles/PMC10378057/ /pubmed/37508581 http://dx.doi.org/10.3390/cells12141918 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Editorial
Klein, Céline
Gindraux, Florelle
Masquelet, Alain-Charles
Mentaverri, Romuald
Gouron, Richard
Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis
title Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis
title_full Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis
title_fullStr Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis
title_full_unstemmed Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis
title_short Questions about Using the Induced Membrane Technique to Manage Cases of Congenital Tibial Pseudarthrosis
title_sort questions about using the induced membrane technique to manage cases of congenital tibial pseudarthrosis
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10378057/
https://www.ncbi.nlm.nih.gov/pubmed/37508581
http://dx.doi.org/10.3390/cells12141918
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